Artikel in Fachzeitschriften: Recent submissions
Now showing items 1401-1420 of 3855
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2018-06-29ZeitschriftenartikelEnvironment Interactions Contribute to Variation in Melanin Production in the Fungal Pathogen Cryptococcus neoformans Cryptococcosis is a common opportunistic fungal infection that often disseminates into the central nervous system, leading to meningitis. Production of melanin pigments during infections is one of the most important virulence ...
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2018-06-15ZeitschriftenartikelAreas with High Hazard Potential for Autochthonous Transmission of Aedes albopictus-Associated Arboviruses in Germany The intensity and extent of transmission of arboviruses such as dengue, chikungunya, and Zika virus have increased markedly over the last decades. Autochthonous transmission of dengue and chikungunya by Aedes albopictus ...
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2018-08-06ZeitschriftenartikelBehavioural and demographic correlates of undiagnosed HIV infection in a MSM sample recruited in 13 European cities Background: Reducing the number of people with undiagnosed HIV infection is a major goal of HIV control and prevention efforts in Europe and elsewhere. We analysed data from a large multi-city European bio-behavioural ...
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2018-08-09ZeitschriftenartikelWhole genome analyses of CMY-2-producing Escherichia coli isolates from humans, animals and food in Germany Background: Resistance to 3rd-generation cephalosporins in Escherichia coli is mostly mediated by extended-spectrum beta-lactamases (ESBLs) or AmpC beta-lactamases. Besides overexpression of the species-specific chromosomal ...
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2018-08-01ZeitschriftenartikelBotulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q58–K59 Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities In the recent past, about 40 botulinum neurotoxin (BoNT) subtypes belonging to serotypes A, B, E, and F pathogenic to humans were identified among hundreds of independent isolates. BoNTs are the etiological factors of ...
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2018-08-06ZeitschriftenartikelThe usefulness of C-reactive protein in predicting malaria parasitemia in a sub-Saharan African region Background: Malaria remains a leading cause of childhood mortality in sub-Saharan Africa. Identifying patients who are at risk for severe manifestations at presentation still remains challenging. This study examines ...
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2018-06-19ZeitschriftenartikelThe PGRS Domain of Mycobacterium tuberculosis PE_PGRS Protein Rv0297 Is Involved in Endoplasmic Reticulum Stress-Mediated Apoptosis through Toll-Like Receptor 4 The genome of Mycobacterium tuberculosis, the causal organism of tuberculosis (TB), encodes a unique protein family known as the PE/PPE/PGRS family, present exclusively in the genus Mycobacterium and nowhere else in the ...
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2018-08-15ZeitschriftenartikelSilent Witness: Dual-Species Transcriptomics Reveals Epithelial Immunological Quiescence to Helminth Larval Encounter and Fostered Larval Development Gastrointestinal nematodes are among the most prevalent parasites infecting humans and livestock worldwide. Infective larvae of the soil-transmitted nematode Ascaris spp. enter the host and start tissue migration by crossing ...
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2018-06-26ZeitschriftenartikelThe RNA Helicase DDX6 Associates with RIG-I to Augment Induction of Antiviral Signaling Virus infections induce sensitive antiviral responses within the host cell. The RNA helicase retinoic acid-inducible gene I (RIG-I) is a key sensor of influenza virus RNA that induces the expression of antiviral type I ...
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2018-05-31ZeitschriftenartikelTravel-associated hepatitis A in Europe, 2009 to 2015 Background: Travel to countries with high or intermediate hepatitis A virus (HAV) endemicity is a risk factor for infection in residents of countries with low HAV endemicity. Aim: The objective of this study was to ...
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2017-05-29ZeitschriftenartikelUmwelteinflüsse medizinisch bewerten Neue Herausforderungen für die Praxis ante portas
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2018-04-20ZeitschriftenartikelIFN-λ and microRNAs are important modulators of the pulmonary innate immune response against influenza A (H1N2) infection in pigs The innate immune system is paramount in the response to and clearance of influenza A virus (IAV) infection in non-immune individuals. Known factors include type I and III interferons and antiviral pathogen recognition ...
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2018-03-27ZeitschriftenartikelRetrospective Analysis of Bacterial Cultures Sampled in German Chicken-Fattening Farms During the Years 2011–2012 Revealed Additional VIM-1 Carbapenemase-Producing Escherichia coli and a Serologically Rough Salmonella enterica Serovar Infantis Carbapenems are last-resort antibiotics used in human medicine. The increased detection of carbapenem-resistant Enterobacteriaceae (CRE) is therefore worrying. In 2011 we reported the first livestock-associated VIM-1-producing ...
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2018-04-03ZeitschriftenartikelMALDI Spectra Database for Rapid Discrimination and Subtyping of Mycobacterium kansasii Mycobacterium kansasii is an emerging non-tuberculous mycobacterial (NTM) pathogen capable of causing severe lung disease. Of the seven currently recognized M. kansasii genotypes (I-VII), genotypes I and II are most prevalent ...
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2018-03-22ZeitschriftenartikelPopulation Genomics of Francisella tularensis subsp. holarctica and its Implication on the Eco-Epidemiology of Tularemia in Switzerland Whole genome sequencing (WGS) methods provide new possibilities in the field of molecular epidemiology. This is particularly true for monomorphic organisms where the discriminatory power of traditional methods (e.g., ...
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2018-04-10ZeitschriftenartikelDisease detection, epidemiology and outbreak response: the digital future of public health practice Inequalities persist when it comes to the attention, resource allocation and political prioritization, and provision of appropriate, adequate, and timely health interventions to populations in need. Set against a complex ...
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2018-03-22ZeitschriftenartikelRapid Viral Diagnosis of Orthopoxviruses by Electron Microscopy: Optional or a Must? Diagnostic electron microscopy (DEM) was an essential component of viral diagnosis until the development of highly sensitive nucleic acid amplification techniques (NAT). The simple negative staining technique of DEM was ...
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2018-03-15ZeitschriftenartikelFind and treat or find and lose? Tuberculosis treatment outcomes among screened newly arrived asylum seekers in Germany 2002 to 2014 Background: Germany has a low tuberculosis (TB) incidence. A relevant and increasing proportion of TB cases is diagnosed among asylum seekers upon screening. Aim: We aimed to assess whether cases identified by screening ...
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2018-03-27ZeitschriftenartikelOccurrence and distribution of Giardia species in wild rodents in Germany Background: Giardiasis is an important gastrointestinal parasitic disease in humans and other mammals caused by the protozoan Giardia duodenalis. This species complex is represented by genetically distinct groups ...
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2018-03-27ZeitschriftenartikelPost-millennial trends of socioeconomic inequalities in chronic illness among adults in Germany Objective: Time trends in health inequalities have scarcely been studied in Germany as only few national data have been available. In this paper, we explore trends in socioeconomic inequalities in the prevalence of ...