Artikel in Fachzeitschriften: Neuzugänge
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2011-12-09ZeitschriftenartikelAbsence of Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex CC398 as a Nasal Colonizer of Pigs Raised in an Alternative System Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) ST398 isolated from pigs raised in conventional farms was previously reported. Here we report a study on 25 farms adhering to an alternative system. ...
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2011-05-31ZeitschriftenartikelImprovement of H5N1 influenza vaccine viruses: Influence of internal gene segments of avian and human origin on production and hemagglutinin content The H5N1-clade 1 influenza vaccine strain NIBRG-14 produces exceptionally low amounts of antigen, a problem recently encountered also for initial pandemic H1N1-2009 vaccine seeds. Here, we report on a strategy that may ...
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2011-11-30ZeitschriftenartikelGenome analysis of bat adenovirus 2: Indications of interspecies transmission The genome of bat adenovirus 2 was sequenced and analyzed. It is similar in size (31,616 bp) to the genomes of bat adenovirus 3 and canine adenoviruses 1 and 2. These four viruses are monophyletic and share an identical ...
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2011-05-30ZeitschriftenartikelApplication of a split luciferase complementation assay for the detection of viral protein–protein interactions Intraviral protein-protein interactions are critical for virus survival in the host. Discovery of such interactions is important to understand molecular mechanisms of viral replication and pathogenesis. The development of ...
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2011-05-25ZeitschriftenartikelPopulation-wide use of behavioural prevention and counselling programmes for lifestyle-related cardiovascular risk factors in Germany Background: Behavioural prevention and counselling programmes for lifestyle-related cardiovascular risk factors are widely offered. However, their population-wide use is largely unexplored, particularly in high-risk persons ...
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2011-06-21ZeitschriftenartikelMolecular characterization of blaNDM-1 in an Acinetobacter baumannii strain isolated in Germany in 2007 Objectives: To investigate the genetic environment of the metallo-β-lactamase gene blaNDM-1 in an Acinetobacter baumannii isolated in 2007 in a German hospital. Methods: Antimicrobial susceptibility testing was performed ...
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2011-06-01ZeitschriftenartikelRNA helicase retinoic acid-inducible gene I as a sensor of Hantaan virus replication Hantaan virus (HTNV) causes severe human disease. The HTNV genome consists of three ssRNA segments of negative polarity that are complexed with viral nucleocapsid (N) protein. How the human innate immune system detects ...
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2012-05-23ZeitschriftenartikelChromosomal Aberrations Associated with Clonal Evolution and Leukemic Transformation in Fanconi Anemia: Clinical and Biological Implications Fanconi anaemia (FA) is an inherited disease with congenital and developmental abnormalities, bone marrow failure, and extreme risk of leukemic transformation. Bone marrow surveillance is an important part of the clinical ...
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2012-07-18ZeitschriftenartikelExpression of XCR1 characterizes the Batf3-dependent lineage of dendritic cells capable of antigen cross-presentation Cross-presentation of antigen by dendritic cells (DCs) to CD8+ T cells is a fundamentally important mechanism in the defense against pathogens and tumors. Due to the lack of an appropriate lineage marker, cross-presenting ...
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2012-08-03ZeitschriftenartikelThe role of the mycobacterial DNA-binding protein 1 (MDP1) from Mycobacterium bovis BCG in host cell interaction Background: Mycobacterium tuberculosis differs from most pathogens in its ability to multiply inside monocytes and to persist during long periods of time within granuloma in a status of latency. A class of proteins ...
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2012-06-19ZeitschriftenartikelHautkrebs – Epidemiologie und Früherkennung
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2012-09-01ZeitschriftenartikelHenipavirus-related Sequences in Fruit Bat Bushmeat, Republic of Congo TO THE EDITOR: Bats are hosts for various emerging viruses, including the zoonotic paramyxoviruses Hendra virus and Nipah virus, which occur in Australia and Southeast Asia, respectively, and cause severe disease outbreaks ...
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2012-09-01ZeitschriftenartikelEffectiveness and Timing of Vaccination during School Measles Outbreak Despite high vaccination coverage in most European countries, large community outbreaks of measles do occur, normally clustered around schools and resulting from suboptimal vaccination coverage. To determine whether or ...
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2011-07-01ZeitschriftenartikelMolecular genotyping and epidemiology of measles virus transmission in the World Health Organization European Region, 2007-2009 Background: In 2002, the World Health Organization (WHO) adopted a goal to eliminate measles in the European Region by 2010. Measles elimination is defined as the interruption of indigenous measles virus (MV) transmission. ...
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2011-02-10ZeitschriftenartikelImmunological properties of the transmembrane envelope protein of the feline foamy virus and its use for serological screening The transmembrane envelope (TM) proteins of retroviruses are used as antigen in diagnostic immunoassays and they represent a conserved target for neutralizing antibodies. To analyze the situation in infections with the ...
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2011-07-01ZeitschriftenartikelCloser to the Goal: Efforts in Measles Elimination in Germany 2010 Increasing 2-dose vaccination coverage has led to an interruption of endemic measles virus circulation in Germany. However, outbreaks after virus importation still occur and contribute to international transmission chains. ...
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2011-08-01ZeitschriftenartikelComparison of direct cultivation on a selective solid medium, polymerase chain reaction from an enrichment broth, and the BD GeneOhm™ VanR Assay for identification of vancomycin-resistant enterococci in screening specimens Fast and reliable diagnostics of vancomycin-resistant enterococci (VRE) is an important prerequisite for containing VRE transmission rates and controlling VRE outbreaks among hospital patients. The BD GeneOhm™ VanR Assay ...
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2010-07-27ZeitschriftenartikelJodmangel im Säuglingsalter - ein Risiko für die kognitive Entwicklung Iodine deficiency in infancy - a risk for cognitive developmentDass ein schwerer Jodmangel während der Schwangerschaft die Gehirnentwicklung des Embryos und Feten gravierend beeinflusst und in extremen Fällen Kretinismus droht, ist bekannt. Neuere Studien belegen, dass sich bereits ...
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2011-08-27ZeitschriftenartikelDiversity of Salmonella enterica serovar Derby isolated from pig, pork and humans in Germany Salmonella enterica serovar Derby (S. Derby) is one of the most prevalent serovars in pigs in Europe and in the U.S. and ranks among the 10 most frequently isolated serovars in humans. Therefore, a set of 82 epidemiologically ...
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2011-07-23ZeitschriftenartikelThe Pathology of Experimental Poxvirus Infection in Common Marmosets (Callithrix jacchus): Further Characterization of a New Primate Model for Orthopoxvirus Infections Zoonotic orthopoxvirus (OPV) can induce severe disease in man and the virus has potential for use in bioterrorism. New vaccines and therapeutics against OPV infections must be tested in animal models. The aim of this study ...