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Anzeige der Publikationen 12121-12140 von 13320
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2011-06-22ZeitschriftenartikelCharacterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study Background: In an ongoing outbreak of haemolytic uraemic syndrome and bloody diarrhoea caused by a virulent Escherichia coli strain O104:H4 in Germany (with some cases elsewhere in Europe and North America), 810 cases ...
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2011-08-15ZeitschriftenartikelHuman endogenous retrovirus K (HERV-K) is expressed in villous and extravillous cytotrophoblast cells of the human placenta Human endogenous retroviruses (HERVs) have been shown to be important in physiological and pathophysiological processes in humans. Several HERVs have been found to be expressed in the placenta—a tissue with special ...
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2011-09-03ZeitschriftenartikelMedical importance of Sindbis virus in south-west Germany
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2011-09-03ZeitschriftenartikelSecond external quality assessment of the molecular diagnostic of West Nile virus: Are there improvements towards the detection of WNV? Background: WNV epidemics occur worldwide, new WNV isolates were isolated in southern-east Europe belonging to WNV lineage 2. A first international proficiency study on WNV indicted that some laboratories were not able ...
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2011-06-12ZeitschriftenartikelHLA class I-associated diseases with a suspected autoimmune etiology: HLA-B27 subtypes as a model system Although most autoimmune diseases are connected to major histocompatibility complex (MHC) class II alleles, a small number of these disorders exhibit a variable degree of association with selected MHC class I genes, like ...
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2012-01-01ZeitschriftenartikelHarnessing prions as test agents for the development of broad-range disinfectants The development of disinfectants with broad-range efficacy against bacteria, viruses, fungi, protozoa and prions constitutes an ongoing challenge. Prions, the causative agents of transmissible spongiform encephalopathies ...
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2012-01-01ZeitschriftenartikelChronic wasting disease: Fingerprinting the culprit in risk assessments Transmissible spongiform encephalopathies (prion diseases) in animals may be associated with a zoonotic risk potential for humans as shown by the occurrence of variant Creutzfeldt-Jakob disease in the wake of the bovine ...
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2011-08-26ZeitschriftenartikelSero-epidemiology of measles-specific IgG antibodies and predictive factors for low or missing titres in a German population-based cross-sectional study in children and adolescents (KiGGS) Background and objective: In the European Region, measles elimination is now targeted to 2015. To measure progress towards elimination age-group specific susceptibility targets have been defined. Age-specific measles ...
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2011-06-12ZeitschriftenartikelPattern of seroreactivity against feline foamy virus proteins in domestic cats from Germany The prevalence of feline foamy virus (FFV, spumaretrovirinae) in naturally infected domestic cats ranges between 30 and 80% FFV positive animals depending on age, sex and geographical region analyzed. Two serotypes have ...
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2012-08-14ZeitschriftenartikelIsolation and characterization of three Mammalian orthoreoviruses from European bats. In recent years novel human respiratory disease agents have been described in South East Asia and Australia. The causative pathogens were classified as pteropine orthoreoviruses with strong phylogenetic relationship to ...
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2012-07-27ZeitschriftenartikelZidovudine Exposure in HIV-1 Infected Tanzanian Women Increases Mitochondrial DNA Levels in Placenta and Umbilical Cords Background: Zidovudine (AZT) constitutes part of the recommended regimens for prevention and treatment of HIV-1 infection. At the same time, AZT as well as HIV-1 infection itself may induce mitochondrial damage. In this ...
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2012-04-06ZeitschriftenartikelOvercoming Species Boundaries in Peptide Identification with Bayesian Information Criterion-driven Error-tolerant Peptide Search (BICEPS) Currently, the reliable identification of peptides and proteins is only feasible when thoroughly annotated sequence databases are available. Although sequencing capacities continue to grow, many organisms remain without ...
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2012-07-05ZeitschriftenartikelFirst report of sandfly fever virus infection imported from Malta into Switzerland, October 2011 We report the first documented cases of sandfly fever virus infection in travellers returning from Malta to Switzerland in autumn 2011. These cases illustrate the importance of considering sandfly-borne viral infection in ...
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2012-06-12ZeitschriftenartikelHigh Prevalence of Giardia duodenalis Assemblage B Infection and Association with Underweight in Rwandan Children Background: Giardia duodenalis is highly endemic in East Africa but its effects on child health, particularly of submicroscopic infections, i.e., those below the threshold of microscopy, and of genetic subgroups ...
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2012-07-02ZeitschriftenartikelHigh Resolution Discrimination of Clinical Mycobacterium tuberculosis Complex Strains Based on Single Nucleotide Polymorphisms Recently, the diversity of the Mycobacterium tuberculosis complex (MTBC) population structure has been described in detail. Based on geographical separation and specific host pathogen co-evolution shaping MTBC virulence ...
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2012-06-29ZeitschriftenartikelRapid and high-throughput detection of highly pathogenic bacteria by Ibis PLEX-ID technology In this manuscript, we describe the identification of highly pathogenic bacteria using an assay coupling biothreat group-specific PCR with electrospray ionization mass spectrometry (PCR/ESI-MS) run on an Ibis PLEX-ID ...
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2012-06-29ZeitschriftenartikelRapid Discrimination of Salmonella enterica Serovar Typhi from Other Serovars by MALDI-TOF Mass Spectrometry Systemic infections caused by Salmonella enterica are an ongoing public health problem especially in Sub-Saharan Africa. Essentially typhoid fever is associated with high mortality particularly because of the increasing ...
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2012-06-13ZeitschriftenartikelMycobacterium tuberculosis DosR Regulon Gene Rv0079 Encodes a Putative, ‘Dormancy Associated Translation Inhibitor (DATIN)’ Mycobacterium tuberculosis is a major human pathogen that has evolved survival mechanisms to persist in an immune-competent host under a dormant condition. The regulation of M. tuberculosis metabolism during latent infection ...
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2012-07-31ZeitschriftenartikelThe FIFA Women’s World Cup in Germany 2011 – A practical example for tailoring an event-specific enhanced infectious disease surveillance system Background: Mass gatherings require a decision from public health authorities on how to monitor infectious diseases during the event. The appropriate level of enhanced surveillance depends on parameters like the scale ...
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2012-08-15ZeitschriftenartikelSeropositivity of Lyme Borreliosis and Associated Risk Factors: A Population-Based Study in Children and Adolescents in Germany (KiGGS) Background: Lyme borreliosis (LB) caused by spirochetes of the Borrelia burgdorferi sensu lato complex is the most common tick-borne disease in the northern hemisphere. Data on the distribution and on risk factors in ...