edoc.rki.de - Open Access Publikationsserver: Neuzugänge
Anzeige der Publikationen 281-300 von 13284
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2026-02-12ZeitschriftenartikelEpidemiologische Untersuchung eines Norovirusausbruchs in Kindergemeinschaftseinrichtungen im Landkreis Göttingen im Jahr 2023
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2024-07-12ZeitschriftenartikelgNOMO2: a comprehensive and modular pipeline for integrated multi-omics analyses of microbiomes Background: In recent years, omics technologies have offered an exceptional chance to gain a deeper insight into the structural and functional characteristics of microbial communities. As a result, there is a growing ...
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2024-08-08ZeitschriftenartikelImpact of reference design on estimating SARS-CoV-2 lineage abundances from wastewater sequencing data Background: Sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA from wastewater samples has emerged as a valuable tool for detecting the presence and relative abundances of SARS-CoV-2 variants ...
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2024-01-19ZeitschriftenartikeltANCHOR cell-based ELISA approach as a surrogate for antigen-coated plates to monitor specific IgG directed to the SARS-CoV-2 receptor-binding domain Enzyme-linked immunosorbent assay (ELISA) systems use plates coated with peptides or expressed and purified proteins to monitor immunoglobulins derived from patient serum. However, there is currently no easy, flexible, and ...
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2024-12-23ZeitschriftenartikelEnd-to-end simulation of nanopore sequencing signals with feed-forward transformers Motivation: Nanopore sequencing represents a significant advancement in genomics, enabling direct long-read DNA sequencing at the single-molecule level. Accurate simulation of nanopore sequencing signals from nucleotide ...
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2024-11-05ZeitschriftenartikelAssociation between Socioeconomic Position of the Family and Adolescent Obesity in Germany—Analysis of the Mediating Role of Familial Determinants Background: Obesity’s negative impact on young people’s health has long been known. The family and its socioeconomic position (SEP) are key determinants in adolescent obesity. However, understanding which familial determinants ...
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2024-01-18ZeitschriftenartikelA look at staphylococci from the one health perspective Staphylococcus aureus and other staphylococcal species are resident and transient multihost colonizers as well as conditional pathogens. Especially S. aureus represents an excellent model bacterium for the “One Health” ...
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2024-02-13ZeitschriftenartikelOutpatient Health Service Utilization Among Adults with Diabetes, Hypertension and Cardiovascular Disease During the COVID-19 Pandemic – Results of Population-Based Surveys in Germany from 2019 to 2021 Purpose: Fear of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and lockdown measures may have an impact on health care utilization particularly for people with chronic diseases. We investigated ...
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2024-07-30ZeitschriftenartikelA nested model for AI design and validation The growing AI field faces trust, transparency, fairness, and discrimination challenges. Despite the need for new regulations, there is a mismatch between regulatory science and AI, preventing a consistent framework. A ...
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2024-01-04ZeitschriftenartikelRecombination-aware phylogenetic analysis sheds light on the evolutionary origin of SARS-CoV-2 SARS-CoV-2 can infect human cells through the recognition of the human angiotensin-converting enzyme 2 receptor. This affinity is given by six amino acid residues located in the variable loop of the receptor binding domain ...
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2024-02-01ZeitschriftenartikelGenomic surveillance of STEC/EHEC infections in Germany 2020 to 2022 permits insight into virulence gene profiles and novel O-antigen gene clusters Shiga toxin-producing E. coli (STEC), including the subgroup of enterohemorrhagic E. coli (EHEC), are important bacterial pathogens which cause diarrhea and the severe clinical manifestation hemolytic uremic syndrome (HUS). ...
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2024-01-11ZeitschriftenartikelDifferent populations of A(H1N1)pdm09 viruses in a patient with hemolytic-uremic syndrome Respiratory viral infections may have different impacts ranging from infection without symptoms to severe disease or even death though the reasons are not well characterized. A patient (age group 5–15 years) displaying ...
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2024-07-10ZeitschriftenartikelEffectiveness and duration of protection of primary and booster immunisation against meningococcal serogroup C disease with meningococcal conjugate C and ACWY vaccines: Systematic review Objectives: To estimate vaccine effectiveness (VE) and duration of protection of single primary and booster immunisation with meningococcal C (MenC) and ACWY (MenACWY) conjugate vaccines in preventing MenC invasive ...
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2024-02-28ZeitschriftenartikelCoordinated inflammatory responses dictate Marburg virus control by reservoir bats Bats are increasingly recognized as reservoirs of emerging zoonotic pathogens. Egyptian rousette bats (ERBs) are the known reservoir of Marburg virus (MARV), a filovirus that causes deadly Marburg virus disease (MVD) in ...
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2023-11-08ZeitschriftenartikelEvaluating the hepatitis B vaccination impact in the Republic of Moldova: A nationwide representative serosurvey of children born in 2013 Objectives: The WHO European Region set targets for the control of hepatitis B through immunization, including prevalence of hepatitis B surface antigen (HBsAg) at ≤0.5% in vaccinated cohorts. The Republic of Moldova ...
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2026-02-11ZeitschriftenartikelARE-Wochenbericht des RKI KW06 Aktuel les zu akuten respi rator ischen Erkrankungen 6. Kalenderwoche (2.2. bis 8.2.2026)Das ARE-Geschehen wird weiterhin durch die Zirkulation von Influenzaviren bestimmt, die Grippewelle hält weiter an. Influenzaerkrankungen betreffen aktuell alle Altersgruppen und führen zu einer hohen Zahl an akuten ...
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2024-02-08ZeitschriftenartikelRSV immunisation in infants: weighing the options
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2024-01-20ZeitschriftenartikelDeveloping a next level integrated genomic surveillance: Advances in the molecular epidemiology of HIV in Germany Advances in the molecular epidemiological studies of the Human Immunodeficiency Virus (HIV) at the Robert Koch Institute (RKI) by laboratory and bioinformatic automation should allow the processing of larger numbers of ...
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2024-03-12ZeitschriftenartikelEstimating the health effects of COVID-19-related immunisation disruptions in 112 countries during 2020–30: a modelling study Background: There have been declines in global immunisation coverage due to the COVID-19 pandemic. Recovery has begun but is geographically variable. This disruption has led to under-immunised cohorts and interrupted ...
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2024-01-24ZeitschriftenartikelCharacteristics of two zoonotic swine influenza A(H1N1) viruses isolated in Germany from diseased patients Interspecies transmission of influenza A viruses (IAV) from pigs to humans is a concerning event as porcine IAV represent a reservoir of potentially pandemic IAV. We conducted a comprehensive analysis of two porcine A(H1N1)v ...