edoc.rki.de - Open Access Publikationsserver: Recent submissions
Now showing items 521-540 of 13427
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2023-02-10ZeitschriftenartikelSelf-rated health of university students in Germany–The importance of material, psychosocial, and behavioral factors and the parental socio-economic status Introduction: Health inequalities start early in life. The time of young adulthood, between late teens and early twenties, is especially interesting in this regard. This time of emerging adulthood, the transition from being ...
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2023-03-27ZeitschriftenartikelFood-Induced Anaphylaxis: Data From the European Anaphylaxis Registry Background: Food is one of the most common elicitors of anaphylaxis, with an increasing incidence over recent years. Objectives: To characterize elicitor-specific phenotypes and identify factors enhancing the risk or ...
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2023-02-09ZeitschriftenartikelQualitative assessment of hand hygiene knowledge, attitudes and practices among healthcare workers prior to the implementation of the WHO Hand Hygiene Improvement Strategy at Faranah Regional Hospital, Guinea Healthcare-associated infections are a serious burden globally. Few qualitative studies have explored healthcare workers’ knowledge, attitudes and practices of hand hygiene. Prior to the implementation of the World Health ...
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2022-11-19ZeitschriftenartikelAnalyses of Basal and Squamous Cell Carcinoma Reported as an Adverse Drug Reaction and Comparison with Cases from the Cancer Registry from Germany Introduction: In Germany, incidence rates of basal cell (BCC) and squamous cell carcinoma (SCC) rose significantly from 1998 to 2010. Ultraviolet (UV) light exposure, immunosuppressants and drugs with photosensitising ...
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2023-09-29ZeitschriftenartikelaKmerBroom: Ancient oral DNA decontamination using Bloom filters on k-mer sets Dental calculus samples are modeled as a mixture of DNA coming from dental plaque and contaminants. Current computational decontamination methods such as Recentrifuge and DeconSeq require either a reference database or ...
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2026-02-04ZeitschriftenartikelPerceived health risks from paid work in Germany in 2014/2015 and 2024 Background: Paid work can have a significant impact on employees’ health. This article describes the perceived health risks associated with paid work in Germany. Methods: Data from full-time and part-time employed persons ...
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2026-02-04ZeitschriftenartikelWahrgenommene Gesundheitsgefährdung durch Erwerbsarbeit in Deutschland in den Jahren 2014/2015 und 2024 Hintergrund: Erwerbsarbeit kann die Gesundheit von Beschäftigten erheblich beeinflussen. Dieser Beitrag beschreibt die wahrgenommene Gesundheitsgefährdung durch Erwerbsarbeit in Deutschland. Methode: Analysiert wurden ...
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2023-11-06ZeitschriftenartikeldecOM: similarity-based microbial source tracking of ancient oral samples using k-mer-based methods Background: The analysis of ancient oral metagenomes from archaeological human and animal samples is largely confounded by contaminant DNA sequences from modern and environmental sources. Existing methods for Microbial ...
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2023-02-22ZeitschriftenartikelDevelopment of a rapid diagnostic test based on loop-mediated isothermal amplification to identify the most frequent non-typhoidal Salmonella serovars from culture Identification of Salmonella serovars is performed by conventional seroagglutination or sequencing. These methods are labor-intensive and require technical experience. An easy-to-perform assay allowing the timely identification ...
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2023-05-26ZeitschriftenartikelM2Q oder doch etwas Anderes? Der Einfluss verschiedener Aufgreifkriterien auf die Prävalenzschätzung chronischer Erkrankungen mit ambulanten GKV-Diagnosedaten Ziele: Zur Ermittlung der Prävalenz von chronischen Erkrankungen auf Basis von ambulanten Krankenkassendaten wird häufig auf eine wiederholte Nennung einer Diagnose im Laufe eines Jahres zurückgegriffen, meist in zwei oder ...
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2023-03-27ZeitschriftenartikelAssembling highly repetitive Xanthomonas TALomes using Oxford Nanopore sequencing Background: Most plant-pathogenic Xanthomonas bacteria harbor transcription activator-like effector (TALE) genes, which function as transcriptional activators of host plant genes and support infection. The entire ...
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2026-01StudienarbeitA Study Using German Cancer Registry Data to Explore the Real-World Patient Characteristics, Treatment Patterns, and Clinical Outcomes in Advanced/Metastatic Gastroesophageal Adenocarcinoma in Germany Die Adenokarzinome des distalen Magens, des proximalen Magens und des gastroösophagealen Übergangs (GEJ) werden gemeinsam als gastroösophageales Adenokarzinom (GEA) bezeichnet. Das lokal fortgeschrittene oder metastasierte ...
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2023-04-14ZeitschriftenartikelPreparing for future European efficacy trials of interventions to prevent HIV and other sexually transmitted infections: Lessons on willingness to participate and barriers to participation from ten German clinics serving behaviorally vulnerable men who have sex with men Future efficacy testing of interventions to prevent HIV or other infections will require engagement of vulnerable populations. We characterized willingness to participate in a future HIV vaccine trial and barriers to ...
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2023-06-22ZeitschriftenartikelStrengthening COVID-19 pandemic response coordination through public health emergency operations centres (PHEOC) in Africa: Review of a multi-faceted knowledge management and sharing approach, 2020–2021 The coronavirus disease 2019 (COVID-19) pandemic disrupted health security program implementation and incremental gains achieved after the West African Ebola outbreak in 2016 across Africa. Following cancellation of in-person ...
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2023-11-21ZeitschriftenartikelInhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent antiviral defense of the lung epithelial barrier SARS-CoV-2 is the causative agent of the immune response-driven disease COVID-19 for which new antiviral and anti-inflammatory treatments are urgently needed to reduce recovery time, risk of death and long COVID development. ...
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2023-11-13ZeitschriftenartikelDo in-person and computer-based brief alcohol interventions reduce tobacco smoking among general hospital patients? Secondary outcomes from a randomized controlled trial Background: At-risk alcohol use and tobacco smoking often co-occur. We investigated whether brief alcohol interventions (BAIs) among general hospital patients with at-risk alcohol use may also reduce tobacco smoking ...
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2023-11-27ZeitschriftenartikelPolicy responses to the COVID-19 pandemic in West Africa: a scoping review protocol Introduction: Four years after the devastating Ebola outbreak, governments in West Africa were quick to implement non-pharmaceutical interventions (NPIs) in response to the rapid spread of SARS-CoV-2. The NPIs implemented ...
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2023-01-17ZeitschriftenartikelComparison of a Genotype 1 and a Genotype 2 Macaque Foamy Virus env Gene Indicates Distinct Infectivity and Cell-Cell Fusion but Similar Tropism and Restriction of Cell Entry by Interferon-Induced Transmembrane Proteins Foamy viruses (FVs) are naturally found in many different animals and also in primates with the notable exception of humans, but zoonotic infections are common. In several species, two different envelope (env) gene sequence ...
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2023-08-23ZeitschriftenartikelSmall proteins in bacteria – Big challenges in prediction and identification Proteins with up to 100 amino acids have been largely overlooked due to the challenges associated with predicting and identifying them using traditional methods. Recent advances in bioinformatics and machine learning, DNA ...
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2023-01-18ZeitschriftenartikelCrystal structures of OrfX1, OrfX2 and the OrfX1–OrfX3 complex from the orfX gene cluster of botulinum neurotoxin E1 Botulinum neurotoxins (BoNTs) are among the most lethal toxins known to humans, comprising seven established serotypes termed BoNT/A–G encoded in two types of gene clusters (ha and orfX) in BoNT-producing clostridia. The ...