edoc.rki.de - Open Access Publikationsserver: Recent submissions
Now showing items 661-680 of 12463
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2024-08-30ZeitschriftenartikelGrippeWeb-Wochenbericht KW 34 Kalenderwoche 34 (19.8. – 25.8.2024), Datenstand: 27.8.2024Die Aktivität akuter Atemwegserkrankungen (ARE-Inzidenz) in der Bevölkerung ist in der 34. KW 2024 im Vergleich zur Vorwoche insgesamt deutlich gestiegen und lag bei rund 4.800 ARE pro 100.000 Einw. (Vorwoche: 3.300). ...
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2022-12-20ZeitschriftenartikelInanspruchnahme des Rettungsdiensts bei Suizidversuchen im Verlauf der SARS-CoV-2-Pandemie Hintergrund Die Pandemie hat zu Veränderungen in der Notfallversorgung mit atypischen Schwankungen der Einsatzzahlen geführt. Dies wurde u. a. mit dem veränderten Verhalten und einem gesteigerten Belastungsempfinden der ...
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2022-05-07ZeitschriftenartikelNewborn screening in Germany
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2022-07-20ZeitschriftenartikelAdaptation of Brucella melitensis Antimicrobial Susceptibility Testing to the ISO 20776 Standard and Validation of the Method Brucellosis, mainly caused by Brucella (B.) melitensis, is associated with a risk of chronification and relapses. Antimicrobial susceptibility testing (AST) standards for B. melitensis are not available, and the agent is ...
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2022-04-14ZeitschriftenartikelMALDI-TOF-MS-Based Identification of Monoclonal Murine Anti-SARS-CoV-2 Antibodies within One Hour During the SARS-CoV-2 pandemic, many virus-binding monoclonal antibodies have been developed for clinical and diagnostic purposes. This underlines the importance of antibodies as universal bioanalytical reagents. However, ...
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2022-06-27ZeitschriftenartikelReadBouncer: precise and scalable adaptive sampling for nanopore sequencing Motivation Nanopore sequencers allow targeted sequencing of interesting nucleotide sequences by rejecting other sequences from individual pores. This feature facilitates the enrichment of low-abundant sequences by ...
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2022-01-05ZeitschriftenartikelHealth data collection methods and procedures across EU member states: findings from the InfAct Joint Action on health information Background Health-related data are collected from a variety of sources for different purposes, including secondary use for population health monitoring (HM) and health system performance assessment (HSPA). Most of these ...
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2022-02-04ZeitschriftenartikelGeographical differences of carbapenem non-susceptible Enterobacterales and Acinetobacter spp. in Germany from 2017 to 2019 Background Since May 2016, infection and colonisation with carbapenem non-susceptible Acinetobacter spp. (CRA) and Enterobacterales (CRE) have to be notified to health authorities in Germany. The aim of our study was ...
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2024-08StudienarbeitSozioökonomische und geografische Unterschiede bei der Erstdiagnose von Krebs in Deutschland Sozioökonomische Ungleichheiten bei den Krebsüberlebensraten sind gut dokumentiert, und Patient*innen, die in benachteiligten Regionen leben, haben niedrigere Überlebensraten. Das Stadium bei der Krebsdiagnose ist ein ...
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2024-08StudienarbeitProspektive Erhebung zur Veränderung der bevorzugten Therapieform beim low risk und favourable intermediate risk Prostatakarzinom in Deutschland (67a-Studie) Die vorliegende Studie soll als epidemiologische Aufarbeitung die tatsächliche Veränderung der bevorzugten Therapieform beim low risk Prostatakarzinom dienen. Um das komplette Bild der Situation in Deutschland zu analysieren, ...
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2022-02-14ZeitschriftenartikelCorrection to: Health data collection methods and procedures across EU member states: findings from the InfAct Joint Action on health information
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2022-09-08ZeitschriftenartikelA large multi-country outbreak of monkeypox across 41 countries in the WHO European Region, 7 March to 23 August 2022 Following the report of a non-travel-associated cluster of monkeypox cases by the United Kingdom in May 2022, 41 countries across the WHO European Region have reported 21,098 cases and two deaths by 23 August 2022. Nowcasting ...
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2022-04-07ZeitschriftenartikelA Conserved Cysteine Residue in Coxsackievirus B3 Protein 3A with Implication for Elevated Virulence Enteroviruses (EV) are implicated in an extensive range of clinical manifestations, such as pancreatic failure, cardiovascular disease, hepatitis, and meningoencephalitis. We recently reported on the biochemical properties ...
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2022-07-30ZeitschriftenartikelRegional disparities in SARS-CoV-2 infections by labour market indicators: a spatial panel analysis using nationwide German data on notified infections Background Regional labour markets and their properties are named as potential reasons for regional variations in levels of SARS-CoV-2 infections rates, but empirical evidence is missing. Methods Using nationwide ...
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2022-12-23ZeitschriftenartikelSocioeconomic differences in the reduction of face-to-face contacts in the first wave of the COVID-19 pandemic in Germany Background The COVID-19 pandemic has led to physical distancing measures to control the spread of SARS-CoV-2. Evidence on contact dynamics in different socioeconomic groups is still sparse. This study aimed to investigate ...
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2022-03-16ZeitschriftenartikelMurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling Gram-positive bacteria are protected by a thick mesh of peptidoglycan (PG) completely engulfing their cells. This PG network is the main component of the bacterial cell wall, it provides rigidity and acts as foundation for ...
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2022-06-10ZeitschriftenartikelAdaptation of Listeria monocytogenes to perturbation of c-di-AMP metabolism underpins its role in osmoadaptation and identifies a fosfomycin uptake system The human pathogen Listeria monocytogenes synthesizes and degrades c-di-AMP using the diadenylate cyclase CdaA and the phosphodiesterases PdeA and PgpH respectively. c-di-AMP is essential because it prevents the uncontrolled ...
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2022-07-07ZeitschriftenartikelRecombinant AcnB, NrdR and RibD of Acinetobacter baumannii and their potential interaction with DNA adenine methyltransferase AamA In the last decades Acinetobacter baumannii developed into an increasingly challenging nosocomial pathogen. A. baumannii ATCC 17978 harbors a DNA-(adenine N6)-methyltransferase termed AamA. Previous studies revealed a low ...
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2022-06-06ZeitschriftenartikelHuman duodenal organoid-derived monolayers serve as a suitable barrier model for duodenal tissue Usually, duodenal barriers are investigated using intestinal cell lines like Caco-2, which in contrast to native tissue are limited in cell-type representation. Organoids can consist of all intestinal cell types and are ...
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2022-09-23ZeitschriftenartikelPhysical Activity Treatment in Adults with Type 2 Diabetes Mellitus per National Treatment Guidelines for Germany: A Telephone-Survey-Based Analysis Physical activity (PA) is effective in the prevention of type 2 diabetes mellitus (T2DM). According to the German national treatment guidelines for T2DM, PA is recommended at all stages of the treatment process. Adults ...