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2014-02-27ZeitschriftenartikelLarge multistate outbreak of norovirus gastroenteritis associated with frozen strawberries, Germany, 2012 From 20 September through 5 October 2012, the largest recorded food-borne outbreak in Germany occurred. Norovirus was identified as the causative agent. We conducted four analytical epidemiological studies, two case–control ...
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2013-02-28ZeitschriftenartikelSelbstberichteter allgemeiner Gesundheitszustand nach Beruf und Alter in der Erwerbsbevölkerung Bei Berufsgruppen wurde der selbstberichtete allgemeine Gesundheitszustand unter besonderer Berücksichtigung des Alters untersucht. Hierzu wurden Daten der repräsentativen Telefonbefragungen GEDA 2009 und 2010 (N = 26.303) ...
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2014-01-10ZeitschriftenartikelHeteropathogenic virulence and phylogeny reveal phased pathogenic metamorphosis in Escherichia coli O2:H6 Extraintestinal pathogenic and intestinal pathogenic (diarrheagenic) Escherichia coli differ phylogenetically and by virulence profiles. Classic theory teaches simple linear descent in this species, where non-pathogens ...
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2013-02-28ZeitschriftenartikelWorkers with a chronic disease and work disability Die Prävalenz chronischer Erkrankungen in der Altersgruppe der 18- bis 65-Jährigen ist hoch. Am häufigsten treten kardiometabolische Störungen und muskuloskeletale Krankheiten auf. In Abhängigkeit von der Erkrankung und ...
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2013-02-28ZeitschriftenartikelAlter, Berufsgruppen und psychisches Wohlbefinden Die vorliegende Studie untersucht das psychische Wohlbefinden in unterschiedlichen Berufsgruppen nach Geschlecht und Alter. Es wurden Daten der Befragung „Gesundheit in Deutschland aktuell“ verwendet, die 2009/2010 vom ...
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2014-03-01ZeitschriftenartikelEstimating the under-reporting of norovirus illness in Germany utilizing enhanced awareness of diarrhoea during a large outbreak of Shiga toxin-producing E. coli O104:H4 in 2011 – a time series analysis Background: Laboratory-confirmed norovirus illness is reportable in Germany since 2001. Reported case numbers are known to be undercounts, and a valid estimate of the actual incidence in Germany does not exist. An ...
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2013-11-12ZeitschriftenartikelState of Knowledge and Data Gaps of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Humans Background: Between September 2012 and 22 October 2013, 144 laboratory-confirmed and 17 probable MERS-CoV cases from nine countries were notified to WHO. Methods: We summarize what is known about the epidemiology, ...
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2014-02-19ZeitschriftenartikelHuman Papillomavirus prevalence and probable first effects of vaccination in 20 to 25 year-old women in Germany: a population-based cross-sectional study via home-based self-sampling Background: Estimates of Human Papillomavirus (HPV) prevalence in a population prior to and after HPV vaccine introduction are essential to evaluate the short-term impact of vaccination. Methods: Between 2010 and ...
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2014-02-11ZeitschriftenartikelHigh prevalence and diversity of species D adenoviruses (HAdV-D) in human populations of four Sub-Saharan countries Background: Human adenoviruses of species D (HAdV-D) can be associated with acute respiratory illness, epidemic keratoconjunctivitis, and gastroenteritis, but subclinical HAdV-D infections with prolonged shedding have ...
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2014-02-01ZeitschriftenartikelVaccination coverage among children in Germany estimated by analysis of health insurance claims data In Germany, the national routine childhood immunization schedule comprises 12 vaccinations. Primary immunizations should be completed by 24 mo of age. However, nationwide monitoring of vaccination coverage (VC) is performed ...
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2014-02-13ZeitschriftenartikelInfluenza vaccine effectiveness estimates in Europe in a season with three influenza type/subtypes circulating: the I-MOVE multicentre case–control study, influenza season 2012/13 In the fifth season of Influenza Monitoring Vaccine Effectiveness in Europe (I-MOVE), we undertook a multicentre case–control study (MCCS) in seven European Union (EU) Member States to measure 2012/13 influenza vaccine ...
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2003-01-01ZeitschriftenartikelExpression of ICOS In Vivo Defines CD4+ Effector T Cells with High Inflammatory Potential and a Strong Bias for Secretion of Interleukin 10 The studies performed to date analyzed the overall participation of the inducible costimulator (ICOS) in model diseases, but did not yield information on the nature and function of ICOS-expressing T cells in vivo. We ...
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2014-02-04ZeitschriftenartikelPhylogenetic Analysis of Staphylococcus aureus CC398 Reveals a Sub-Lineage Epidemiologically Associated with Infections in Horses In the early 2000s, a particular MRSA clonal complex (CC398) was found mainly in pigs and pig farmers in Europe. Since then, CC398 has been detected among a wide variety of animal species worldwide. We investigated the ...
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2014-02-05ZeitschriftenartikelHuman Metapneumovirus: Insights from a Ten-Year Molecular and Epidemiological Analysis in Germany Human metapneumovirus (HMPV) is a cause of respiratory tract illness at all ages. In this study the epidemiological and molecular diversity among patients of different ages was investigated. Between 2000–2001 and 2009–2010, ...
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2014-01-30ZeitschriftenartikelInternet-based syndromic monitoring of acute respiratory illness in the general population of Germany, weeks 35/2011 to 34/2012 In March 2011, the German sentinel surveillance system for influenza (Arbeitsgemeinschaft Influenza (AGI)) was complemented by an Internet-based syndromic monitoring system (GrippeWeb) for acute respiratory infections (ARI) ...
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2013-06-21ZeitschriftenartikelPopulation structure of Salmonella enterica serovar 4,[5],12:b:- strains and likely sources of human infection Salmonella enterica serovar 4,[5],12:b:- is a monophasic serovar not able to express the second-phase flagellar antigen (H2 antigen). In Germany, the serovar is occasionally isolated from poultry, reptiles, fish, food, and ...
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2013-02-04ZeitschriftenartikelRecombinant production of Yersinia enterocolitica pyruvate kinase isoenzymes PykA and PykF The glycolytic enzyme pyruvate kinase (PK) generates ATP from ADP through substrate-level phosphorylation powered by the conversion of phosphoenolpyruvate to pyruvate. In contrast to other bacteria, Enterobacteriaceae, ...
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2013-02-01ZeitschriftenartikelAcute gastrointestinal illness in adults in Germany: a population-based telephone survey Population-based estimates of incidence and risk factors for acute gastrointestinal illness (AGI) are important for infectious disease surveillance and healthcare planning. We conducted a nationwide representative ...
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2013-01-18ZeitschriftenartikelFirst indication for a functional CRISPR/Cas system in Francisella tularensis Francisella tularensis is a zoonotic agent and the subspecies novicida is proposed to be a water-associated bacterium. The intracellular pathogen F. tularensis causes tularemia in humans and is known for its potential to ...
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2013-07-12ZeitschriftenartikelDNA Uptake by the Nosocomial Pathogen Acinetobacter baumannii Occurs during Movement along Wet Surfaces The emergence of Acinetobacter baumannii as an increasingly multidrug-resistant nosocomial pathogen largely relies on acquisition of resistance genes via horizontal gene transfer. Here, we demonstrate that many clinical ...