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2024-03-27ZeitschriftenartikelGene knock-out in Mycobacterium abscessus using Streptococcus thermophilus CRISPR/Cas The CRISPRi system using dCas9Sth1 from Streptococcus thermophilus developed for Mycobacterium tuberculosis and M. smegmatis was modified to allow gene knock-out in M. abscessus. Efficacy of the knock-out system was evaluated ...
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2024-08-14ZeitschriftenartikelSozial gerecht: Gesundheit – Umwelt – Klima Tagungsbericht zum Kongress Armut und Gesundheit 2024
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2024-01-20ZeitschriftenartikelGenome sequencing of the mpox virus 2022 outbreak with amplicon-based Oxford Nanopore MinION sequencing We present an amplicon-based assay for MinION Nanopore sequencing of mpox virus (MPXV) genomes from clinical specimens, obtaining high-quality results with an average genome coverage of 99% for Ct values of up to 25, and ...
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2024-02-26ZeitschriftenartikelListening to the Voices of Health Care Workers During the COVID-19 Pandemic: A Qualitative Study Providing In-Depth Insights Into Ethical and Individual Challenges In their daily practice, health care workers (HCWs) experience the effects of tensions between professional ethos and work realities, which can lead to ethical dilemmas. We aim to explore the ethical dilemmas that affected ...
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2023-12-22ZeitschriftenartikelStructure–function relationships underpin disulfide loop cleavage-dependent activation of Legionella pneumophila lysophospholipase A PlaA Legionella pneumophila, the causative agent of a life-threatening pneumonia, intracellularly replicates in a specialized compartment in lung macrophages, the Legionella-containing vacuole (LCV). Secreted proteins of the ...