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2024-04-24Zeitschriftenartikel

Follow-up SARS-CoV-2 serological study of a health care worker cohort following COVID-19 booster vaccination

Hönning, Alexander; Tomczyk, Sara; Hermes, Julia; Grossegesse, Marica; Hofmann, Natalie; Michel, Janine; Neumann, Markus; Nitsche, Andreas; Hoppe, Berthold; Eckmanns, Tim; Schmidt-Traub, Hajo; Zappel, Kristina

Background: Studies have shown that Omicron breakthrough infections can occur at higher SARS-CoV-2 antibody levels compared to previous variants. Estimating the magnitude of immunological protection induced from COVID-19 ...
2024-10-14Zeitschriftenartikel

Diagnostic serology test comparison for Q fever and Rift Valley fever in humans and livestock from pastoral communities

Hungerbühler, Valerie; Özcelik, Ranya; Abakar, Mahamat Fayiz; Abdelrazak Zakaria, Fatima; Eiden, Martin; Hartnack, Sonja; Kimala, Pidou; Kittl, Sonja; Michel, Janine; Suter-Riniker, Franziska; Dürr, Salome

Q fever (QF) and Rift Valley fever (RVF) are endemic zoonotic diseases in African countries, causing significant health and economic burdens. Accurate prevalence estimates, crucial for disease control, rely on robust ...
2024-05-31Zeitschriftenartikel

Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models

Hynds, Robert E.; Huebner, Ariana; Pearce, David R.; Hill, Mark S.; Akarca, Ayse U.; Moore, David A.; Ward, Sophia; Gowers, Kate H. C.; Karasaki, Takahiro; Al Bakir, Maise; Wilson, Gareth A.; Pich, Oriol; Martínez-Ruiz, Carlos; Md Mukarram Hossain, A. S.; Pearce, Simon P.; Sivakumar, Monica; Ben Aissa, Assma; Grönroos, Eva; Chandrasekharan, Deepak; Kolluri, Krishna K.; Towns, Rebecca; Wang, Kaiwen; Cook, Daniel E.; Bosshard-Carter, Leticia; Naceur-Lombardelli, Cristina; Rowan, Andrew J.; Verriah, Selvaraju; Litchfield, Kevin; Crosbie, Philip A. J.; Dive, Caroline; Quezada, Sergio A.; Janes, Sam M.; Jamal-Hanjani, Mariam; Marafioti, Teresa; TRACERx consortium; McGranahan, Nicholas

Patient-derived xenograft (PDX) models are widely used in cancer research. To investigate the genomic fidelity of non-small cell lung cancer PDX models, we established 48 PDX models from 22 patients enrolled in the TRACERx ...
2024-06-05Zeitschriftenartikel

Strategies to foster community engagement for epidemic and pandemic preparedness and response in sub-Saharan Africa: a scoping review protocol

Issahaku, Gyesi Razak; Fischer, Hanna-Tina; Appiah-Brempong, Emmanuel; Opoku, Daniel; Hanefeld, Johanna

Introduction: The surge of public health emergencies over the past decade has disproportionately affected sub-Saharan Africa. These include outbreaks of infectious diseases such as Ebola, Monkeypox and COVID-19. Experience ...
2024-09-26Zeitschriftenartikel

In the Shadow of the Pandemic: Examining Therapists’ Perceptions of Work-Related Stress in the Late Stages of the COVID-19 Pandemic in Germany

Johann, Smilla; Evans, Megan; Böttcher, Rike; Muller, Nadine; Buchberger, Barbara; El Bcheraoui, Charbel; Weishaar, Heide

Background/Objectives: The previous literature has identified increased work-related stress among healthcare workers (HCWs) during the COVID-19 pandemic. This study analyzes work-related perceived stress experienced by ...