Browsing Artikel in Fachzeitschriften by Title
Now showing items 1091-1110 of 4513
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2007-09-06ZeitschriftenartikelDiscovery of herpesviruses in multi-infected primates using locked nucleic acids (LNA) and a bigenic PCR approach Targeting the highly conserved herpes DNA polymerase (DPOL) gene with PCR using panherpes degenerate primers is a powerful tool to universally detect unknown herpesviruses. However, vertebrate hosts are often infected with ...
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2014-12-19ZeitschriftenartikelDiscrete and overlapping functions of peptidoglycan synthases in growth, cell division and virulence of Listeria monocytogenes Upon ingestion of contaminated food, Listeria monocytogenes can cause serious infections in humans that are normally treated with β-lactam antibiotics. These target Listeria's five high molecular weight penicillin-binding ...
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2020-05-22ZeitschriftenartikelDiscrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow At present, it is not clear how memory B lymphocytes are maintained over time, and whetheronly as circulating cells or also residing in particular tissues. Here we describe distinctpopulations of isotype-switched memory B ...
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2018-04-10ZeitschriftenartikelDisease detection, epidemiology and outbreak response: the digital future of public health practice Inequalities persist when it comes to the attention, resource allocation and political prioritization, and provision of appropriate, adequate, and timely health interventions to populations in need. Set against a complex ...
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2023-02-10ZeitschriftenartikelDisease severity in hospitalized COVID-19 patients: comparing routine surveillance with cohort data from the LEOSS study in 2020 in Germany Introduction Studies investigating risk factors for severe COVID-19 often lack information on the representativeness of the study population. Here, we investigate factors associated with severe COVID-19 and compare the ...
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2021-11-12Berichte und sonstige TexteDisease severity of the first COVID-19 wave in Germany using reporting data from the national notification system As of December 31, 2019, initial reports circulated internationally of an unusual cluster of pneumonia of unknown cause in China. By the end of January 2020, the virus affected Germany with the first case confirmed on ...
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2021-05-14ZeitschriftenartikelDisease surveillance for the COVID-19 era: time for bold changes The COVID-19 pandemic has exposed weaknesses in disease surveillance in nearly all countries. Early identification of COVID-19 cases and clusters for rapid containment was hampered by inadequate diagnostic capacity, ...
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2016-01-04ZeitschriftenartikelDisease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma In 1982, the term “prions” (proteinaceous infectious particles) was coined to specify a new principle of infection. A misfolded isoform of a cellular protein has been described as the causative agent of a fatal neurodegenerative ...
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2011-12-28ZeitschriftenartikelDiseases and causes of death in European bats: dynamics in disease susceptibility and infection rates. Background: Bats receive increasing attention in infectious disease studies, because of their well recognized status as reservoir species for various infectious agents. This is even more important, as bats with their ...
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2020-02-05ZeitschriftenartikelDisentangling outbreaks using whole-genome sequencing: concurrent multistate outbreaks of Salmonella Kottbus in Germany, 2017 In June 2017, an outbreak of Salmonella Kottbus infection was suspected in Germany. We investigated the outbreak with whole-genome sequencing (WGS) and a case–control study. Forty-six isolates from 69 cases were subtyped. ...
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2020-05-30ZeitschriftenartikelDisseminated coccidioidomycosis: Monitoring of serologic markers for treatment response We describe a patient with a disseminated coccidioidomycosis. Biomarkers in serum during itraconazole therapy showed a rapid clearing of Coccidioides DNA as detected by PCR. Coccidioides antibody detection by lateral flow ...
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2019-07-25ZeitschriftenartikelDisseminated Emergomycosis in a Person with HIV Infection, Uganda We describe emergomycosis in a patient in Uganda with HIV infection. We tested a formalin-fixed, paraffin-embedded skin biopsy to identify Emergomyces pasteurianus or a closely related pathogen by sequencing broad-range ...
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2018-01-31ZeitschriftenartikelDisseminating Metaproteomic Informatics Capabilities and Knowledge Using the Galaxy-P Framework The impact of microbial communities, also known as the microbiome, on human health and the environment is receiving increased attention. Studying translated gene products (proteins) and comparing metaproteomic profiles may ...
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2013-07-16ZeitschriftenartikelDistal and Proximal Factors of Health Behaviors and Their Associations with Health in Children and Adolescents Objective: The aim of the present paper was to analyze factors affecting distal and proximal health behavior within a biopsychosocial model for examining their interactions and associations with respect to health. Methods: ...
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2023-02-11ZeitschriftenartikelDistinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19 Prolonged lung pathology has been associated with COVID-19, yet the cellular and molecular mechanisms behind this chronic inflammatory disease are poorly understood. In this study, we combine advanced imaging and spatial ...
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2014-05-09ZeitschriftenartikelDistinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop Background: West Nile Virus (WNV) is an emerging mosquito-transmitted flavivirus that continues to spread and cause disease throughout several parts of the world, including Europe and the Americas. Specific diagnosis ...
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2009-04-22ZeitschriftenartikelDistribution and expression of porcine endogenous retroviruses in multi-transgenic pigs generated for xenotransplantation Background: Multi-transgenic pigs produced for use in xenotransplantation have to be screened for the presence and expression of porcine endogenous retroviruses (PERV) to select animals with low PERV load. The production ...
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2018-02-06ZeitschriftenartikelDistribution of Porcine Cytomegalovirus in Infected Donor Pigs and in Baboon Recipients of Pig Heart Transplantation The porcine cytomegalovirus (PCMV) is a herpesvirus that may pose a risk for xenotransplantation using pig cells, tissues, or organs. Here, three orthotopic pig heart transplantations into baboons were studied. To detect ...
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2017-11-24ZeitschriftenartikelDisulfide loop cleavage of Legionella pneumophila PlaA boosts lysophospholipase A activity L. pneumophila, an important facultative intracellular bacterium, infects the human lung and environmental protozoa. At least fifteen phospholipases A (PLA) are encoded in its genome. Three of which, namely PlaA, PlaC, and ...
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2012-05-01ZeitschriftenartikelDiversity of parvovirus 4-like viruses in humans, chimpanzees, and monkeys in hunter-prey relationships. During 2010–2011, we investigated interspecies transmission of partetraviruses between predators (humans and chimpanzees) and their prey (colobus monkeys) in Côte d’Ivoire. Despite widespread infection in all species ...