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2024-09-11Zeitschriftenartikel

Building a High-Level Isolation Unit in Rwanda and Establishing a Training Program for the Medical Management of Patients With High-Consequence Infectious Diseases

Uhrig, Alexander; Rwagasore, Edson; Liebau, Laura Dorothea; Villinger, David; Gertler, Maximilian; Masaisa, Florence; Bitunguhari, Leopold; Piening, Turid; Paerisch, Thomas; Cronen, Thomas; Nkeshimana, Menelas; Muvunyi, Claude Mambo; Stegemann, Miriam Songa

Rwanda is a country in East Africa, a region characterized by highly mobile populations and outbreaks of high-consequence infectious diseases occurring on a regular basis. To increase the level of outbreak preparedness in ...
2024-02-20Zeitschriftenartikel

Nanopore adaptive sampling effectively enriches bacterial plasmids

Ulrich, Jens-Uwe; Epping, Lennard; Pilz, Tanja; Walther, Birgit; Stingl, Kerstin; Semmler, Torsten; Renard, Bernhard Y.

Bacterial plasmids play a major role in the spread of antibiotic resistance genes. However, their characterization via DNA sequencing suffers from the low abundance of plasmid DNA in those samples. Although sample preparation ...
2024-12-20Zeitschriftenartikel

Phenotypic and Genomic Characterization of ESBL- and AmpC-β-Lactamase-Producing Enterobacterales Isolates from Imported Healthy Reptiles

Unger, Franziska; Eisenberg, Tobias; Prenger-Berninghoff, Ellen; Leidner, Ursula; Semmler, Torsten; Ewers, Christa

Background/Objectives: Reptiles are known reservoirs for members of the Enterobacterales. We investigated antimicrobial resistance (AMR) patterns, the diversity of extended-spectrum-/AmpC-β-lactamases (ESBL/AmpC) genes and ...
2024-09-06Zeitschriftenartikel

Susceptibility and infectiousness of SARS-CoV-2 in children versus adults, by variant (wild-type, alpha, delta): A systematic review and meta-analysis of household contact studies

Uthman, Olalekan A.; Plesner Lyngse, Frederik; Anjorin, Seun; Hauer, Barbara; Hakki, Seran; Martinez, Diego A.; Ge, Yang; Jonnerby, Jakob; Halle Julin, Cathinka; Lin, Gary; Lalvani, Ajit; Loss, Julika; Madon, Kieran J.; Martinez, Leonardo; Meyer Næss, Lisbeth; Page, Kathleen R.; Prieto, Diana; Hayman Robertson, Anna; Shen, Ye; Wurm, Juliane; Buchholz, Udo

Importance: Understanding the susceptibility and infectiousness of children and adolescents in comparison to adults is important to appreciate their role in the COVID-19 pandemic. Objective: To determine SARS-CoV-2 ...
2024-06-24Zeitschriftenartikel

Prevalence of HIV in people with potential HIV-indicator conditions in Germany: an analysis of data from statutory health insurances

Valbert, Frederik; Behrens, Georg M. N.; Bickel, Markus; Boesecke, Christoph; Esser, Stefan; Dröge, Patrik; Ruhnke, Thomas; Krings, Amrei; Schmidt, Daniel; Koppe, Uwe; Gunsenheimer-Bartmeyer, Barbara; Wienholt, Lea; Wasem, Jürgen; Neumann, Anja

Background: In care of people living with human immunodeficiency virus (HIV), early diagnosis of infection is one of the greatest challenges remaining. A promising approach to increase early diagnosis could be optimized ...