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2024-05-09ZeitschriftenartikelLRBA, a BEACH protein mutated in human immune deficiency, is widely expressed in epithelia, exocrine and endocrine glands, and neurons Mutations in LRBA, a BEACH domain protein, cause severe immune deficiency in humans. LRBA is expressed in many tissues and organs according to biochemical analysis, but little is known about its cellular and subcellular ...
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2024-10-22ZeitschriftenartikelBrucella microti and Rodent-Borne Brucellosis: A Neglected Public Health Threat Brucellosis is one of the most important zoonoses worldwide, primarily affecting livestock but also posing a serious threat to public health. The major Brucella species are known to cause a feverish disease in humans with ...
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2024-01-06ZeitschriftenartikelFunctional host-specific adaptation of the intestinal microbiome in hominids Fine-scale knowledge of the changes in composition and function of the human gut microbiome compared that of our closest relatives is critical for understanding the evolutionary processes underlying its developmental ...
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2024-08-24ZeitschriftenartikelMachine learning methods for compound annotation in non-targeted mass spectrometry—A brief overview of fingerprinting, in silico fragmentation and de novo methods Non-targeted screenings (NTS) are essential tools in different fields, such as forensics, health and environmental sciences. NTSs often employ mass spectrometry (MS) methods due to their high throughput and sensitivity in ...
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2024-02-20ZeitschriftenartikelGenomic insights into virulence, antimicrobial resistance, and adaptation acumen of Escherichia coli isolated from an urban environment Populations of common commensal bacteria such as Escherichia coli undergo genetic changes by the acquisition of certain virulence and antimicrobial resistance (AMR) encoding genetic elements leading to the emergence of ...
