Browsing Artikel in Fachzeitschriften by Subject "Bacterial Proteins/genetics"
Now showing items 1-20 of 23
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2015-04-09ZeitschriftenartikelA Gateway-Based System for Fast Evaluation of Protein-Protein Interactions in Bacteria Protein-protein interactions are important layers of regulation in all kingdoms of life. Identification and characterization of these interactions is one challenging task of the post-genomic era and crucial for understanding ...
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2009-05-01ZeitschriftenartikelbdhA-patD operon as a virulence determinant, revealed by a novel large-scale approach for identification of Legionella pneumophila mutants defective for amoeba infection. Legionella pneumophila, the causative agent of Legionnaires' disease, is an intracellular parasite of eukaryotic cells. In the environment, it colonizes amoebae. After being inhaled into the human lung, the bacteria infect ...
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2009-11-13ZeitschriftenartikelControl of Flagellar Gene Regulation in Legionella pneumophila and Its Relation to Growth Phase The bacterial pathogen Legionella pneumophila responds to environmental changes by differentiation. At least two forms are well described: replicative bacteria are avirulent; in contrast, transmissive bacteria express ...
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2015-06-16ZeitschriftenartikelCross talk between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa Two-component systems (TCS) serve as stimulus-response coupling mechanisms to allow organisms to adapt to a variety of environmental conditions. The opportunistic pathogen Pseudomonas aeruginosa encodes for more than 100 ...
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2009-02-25ZeitschriftenartikelCross-talk between type three secretion system and metabolism in Yersinia. Pathogenic yersiniae utilize a type three secretion system (T3SS) to inject Yop proteins into host cells in order to undermine their immune response. YscM1 and YscM2 proteins have been reported to be functionally equivalent ...
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2012-10-03ZeitschriftenartikelDirect Detection and Genotyping of KPC Carbapenemases from Urine using a new DNA Microarray Test Klebsiella pneumoniae carbapenemases (KPC) are considered a serious threat to antibiotic therapy as they confer resistance to carbapenems, which are used to treat Extended-spectrum beta-lactamase (ESBL) producing bacteria. ...
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2013-07-12ZeitschriftenartikelDNA Uptake by the Nosocomial Pathogen Acinetobacter baumannii Occurs during Movement along Wet Surfaces The emergence of Acinetobacter baumannii as an increasingly multidrug-resistant nosocomial pathogen largely relies on acquisition of resistance genes via horizontal gene transfer. Here, we demonstrate that many clinical ...
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2011-09-15ZeitschriftenartikelEmergence of bla CTX-M-15, qnrB1 and aac(6′)-ib-cr resistance genes in Pantoea agglomerans and enterobacter cloacae from Nigeria (sub-Saharan Africa) Besides hyper-production of chromosomal AmpC β-lactamases, the expression of plasmid-encoded extended-spectrum β-lactamases (ESBL) in Enterobacter spp has increased in recent years. In this study, we characterized 10 ...
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2012-01-30ZeitschriftenartikelEmergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals Nine carbapenem-resistant Enterobacteriaceae isolates collected from eight patients in five German hospitals were investigated. Six isolates produced the OXA-48 carbapenemase, and three isolates produced OXA-162, which is ...
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2007-05-25ZeitschriftenartikelFepA- and TonB-dependent bacteriophage H8: receptor binding and genomic sequence. H8 is derived from a collection of Salmonella enterica serotype Enteritidis bacteriophage. Its morphology and genomic structure closely resemble those of bacteriophage T5 in the family Siphoviridae. H8 infected S. enterica ...
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2012-08-05ZeitschriftenartikelFliA expression analysis and influence of the regulatory proteins RpoN, FleQ and FliA on virulence and in vivo fitness in Legionella pneumophila In Legionella pneumophila, the regulation of the flagellum and the expression of virulence traits are linked. FleQ, RpoN and FliA are the major regulators of the flagellar regulon. We demonstrated here that all three ...
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2014-12-04ZeitschriftenartikelLow Rates of Antimicrobial-Resistant Enterobacteriaceae in Wildlife in Taï National Park, Côte d’Ivoire, Surrounded by Villages with High Prevalence of Multiresistant ESBL-Producing Escherichia coli in People and Domestic Animals Antimicrobial resistance genes can be found in all ecosystems, including those where antibiotic selective pressure has never been exerted. We investigated resistance genes in a collection of faecal samples of wildlife ...
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2013-08-08ZeitschriftenartikelLPS Structure and PhoQ Activity Are Important for Salmonella Typhimurium Virulence in the Gallleria mellonella Infection Model The larvae of the wax moth, Galleria mellonella, have been used experimentally to host a range of bacterial and fungal pathogens. In this study we evaluated the suitability of G. mellonella as an alternative animal model ...
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2012-06-13ZeitschriftenartikelMycobacterium tuberculosis DosR Regulon Gene Rv0079 Encodes a Putative, ‘Dormancy Associated Translation Inhibitor (DATIN)’ Mycobacterium tuberculosis is a major human pathogen that has evolved survival mechanisms to persist in an immune-competent host under a dormant condition. The regulation of M. tuberculosis metabolism during latent infection ...
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2011-09-08ZeitschriftenartikelPasteurella multocida Involved in Respiratory Disease of Wild Chimpanzees Pasteurella multocida can cause a variety of diseases in various species of mammals and birds throughout the world but nothing is known about its importance for wild great apes. In this study we isolated P. multocida from ...
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2012-08-15ZeitschriftenartikelPerformance of three chromogenic VRE screening agars, two Etest® vancomycin protocols, and different microdilution methods in detecting vanB genotype Enterococcus faecium with varying vancomycin MICs Frequencies of vanB-type Enterococcus faecium increased in Europe during the last years. VanB enterococci show various levels of vancomycin MICs even below the susceptible breakpoint challenging a reliable diagnostics. The ...
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2010-05-14ZeitschriftenartikelPork contaminated with Salmonella enterica serovar 4,[5],12:i:-, an emerging health risk for humans. Salmonella enterica subsp. enterica serovar 4,[5],12:i:- is a monophasic variant of S. enterica serovar Typhimurium (antigenic formula 4,[5],12:i:1,2). Worldwide, especially in several European countries and the United ...
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2011-09-08ZeitschriftenartikelRare Occurrence of Methicillin-Resistant Staphylococcus aureus CC130 with a Novel mecA Homologue in Humans in Germany MRSA CC130 containing the mecA homologue mecALGA251 were reported from the UK and from Denmark so far from cattle and humans. Here we report on 11 MRSA CC130 among a sample of 12691 isolates of human origin collected from ...
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2009-09-01ZeitschriftenartikelSalmonella enterica Serovar Typhi with CTX-M β-Lactamase, Germany
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2007-06-01ZeitschriftenartikelSuccessful termination of a furunculosis outbreak due to lukS-lukF-positive, methicillin-susceptible Staphylococcus aureus in a German village by stringent decolonization, 2002-2005 Background: Skin infections due to Staphylococcus aureus have recently become a public concern, mainly because of emerging resistance against widely used antibiotics and specific virulence determinants. Strains harboring ...