edoc.rki.de - Open Access Publikationsserver: Neuzugänge
Anzeige der Publikationen 7101-7120 von 12694
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2018-05-09ZeitschriftenartikelIs there a duty to participate in digital epidemiology? This paper poses the question of whether people have a duty to participate in digital epidemiology. While an implied duty to participate has been argued for in relation to biomedical research in general, digital epidemiology ...
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2018-05-10ZeitschriftenartikelDraft Genome Sequences of Plant-Associated Bacillus Strains Isolated from the Qinghai-Tibetan Plateau Here, we report the draft genome sequences of 45 plant-associated Bacillus strains isolated from the Qinghai-Tibetan plateau. According to their genome sequences, 28 isolates were assigned to 10 Bacillus species. Seventeen ...
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2018-05-02ZeitschriftenartikelA lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency The exceptional toxicity of botulinum neurotoxins (BoNTs) is mediated by high avidity binding to complex polysialogangliosides and intraluminal segments of synaptic vesicle proteins embedded in the presynaptic membrane. ...
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2018-05-15ZeitschriftenartikelImmunity levels to poliovirus in Lao children and adults before the vaccine-derived poliovirus outbreak: A retrospective study In 2015, several provinces in Lao People's Democratic Republic (Lao PDR) experienced a vaccine-derived poliovirus outbreak. This survey was conducted (i) to evaluate the vaccination coverage in different settings and cohorts ...
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2018-05-02ZeitschriftenartikelGenome-based analysis of Carbapenemase-producing Klebsiella pneumoniae isolates from German hospital patients, 2008-2014 Background By using whole genome sequence data we aimed at describing a population snapshot of carbapenemase-producing K. pneumoniae isolated from hospitalized patients in Germany between 2008 and 2014. Methods We ...
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2018-04-19ZeitschriftenartikelOptimisation of quantitative miRNA panels to consolidate the diagnostic surveillance of HBV-related hepatocellular carcinoma Background: Circulating microRNAs (miRNA) are biomarkers for several neoplastic diseases, including hepatocellular carcinoma (HCC). We performed a literature search, followed by experimental screening and validation in ...
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2018-02-24ZeitschriftenartikelThe use of high-throughput sequencing to investigate an outbreak of glycopeptide-resistant Enterococcus faecium with a novel quinupristin-dalfopristin resistance mechanism High-throughput sequencing (HTS) has successfully identified novel resistance genes in enterococci and determined clonal relatedness in outbreak analysis. We report the use of HTS to investigate two concurrent outbreaks ...
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2018-09-12Heft oder Ausgabe einer ZeitschriftBericht zur Epidemiologie der Influenza in Deutschland Saison 2017/18 Im Bericht zur Epidemiologie der Influenza in Deutschland werden jedes Jahr die Ergebnisse der Influenzaüberwachung des RKI zusammengefasst. Zentraler Bestandteil für die Bewertung sind die Ergebnisse der syndromischen ...
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2017-09-22ZeitschriftenartikelWild rodents and shrews are natural hosts of Staphylococcus aureus Laboratory mice are the most commonly used animal model for Staphylococcus aureus infection studies. We have previously shown that laboratory mice from global vendors are frequently colonized with S. aureus. Laboratory ...
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2018-01-24ZeitschriftenartikelComparative analysis of Salivette® and paraffin gum preparations for establishment of a metaproteomics analysis pipeline for stimulated human saliva The value of saliva as a diagnostic tool can be increased by taxonomic and functional analyses of the microbiota as recently demonstrated. In this proof-of-principle study, we compare two collection methods (Salivette® ...
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2017-11-24ZeitschriftenartikelAureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community In light of continuously accumulating data and knowledge on major human pathogens, comprehensive and up-to-date sources of easily accessible information are urgently required. The AureoWiki database (http://aureowiki.med ...
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2018-07-25ZeitschriftenartikelCytomegalovirus (CMV) seroprevalence in the adult population of Germany Background: Infection with cytomegalovirus (CMV) remains asymptomatic in most immunocompetent hosts, but is the leading cause of congenital viral infection worldwide and can be life-threatening in immunocompromised ...
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2018-07-30ZeitschriftenartikelIntracellular membranes of bacterial endospores are reservoirs for spore core membrane expansion during spore germination Bacterial endospores are formed by certain bacteria, such as Bacillus subtilis or the pathogenic Bacillus anthracis and Clostridioides difficile, to allow survival in environmental conditions which are lethal to vegetative ...
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2018-03-17ZeitschriftenartikelScreening of migrants for tuberculosis identifies patients with multidrug-resistant tuberculosis but is not sufficient
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2018-07-06ZeitschriftenartikelImplications of standardization of serum 25-hydroxyvitamin D data for the evaluation of vitamin D status in Germany, including a temporal analysis Background: Comparability of 25-hydroxyvitamin D (25(OH)D) measurements is hampered by method-related differences in measurement values. International standardization of laboratory assays has been suggested to solve ...
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2018-06-29ZeitschriftenartikelEnvironment Interactions Contribute to Variation in Melanin Production in the Fungal Pathogen Cryptococcus neoformans Cryptococcosis is a common opportunistic fungal infection that often disseminates into the central nervous system, leading to meningitis. Production of melanin pigments during infections is one of the most important virulence ...
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2018-06-15ZeitschriftenartikelAreas with High Hazard Potential for Autochthonous Transmission of Aedes albopictus-Associated Arboviruses in Germany The intensity and extent of transmission of arboviruses such as dengue, chikungunya, and Zika virus have increased markedly over the last decades. Autochthonous transmission of dengue and chikungunya by Aedes albopictus ...
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2018-08-06ZeitschriftenartikelBehavioural and demographic correlates of undiagnosed HIV infection in a MSM sample recruited in 13 European cities Background: Reducing the number of people with undiagnosed HIV infection is a major goal of HIV control and prevention efforts in Europe and elsewhere. We analysed data from a large multi-city European bio-behavioural ...
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2018-08-09ZeitschriftenartikelWhole genome analyses of CMY-2-producing Escherichia coli isolates from humans, animals and food in Germany Background: Resistance to 3rd-generation cephalosporins in Escherichia coli is mostly mediated by extended-spectrum beta-lactamases (ESBLs) or AmpC beta-lactamases. Besides overexpression of the species-specific chromosomal ...
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2018-08-01ZeitschriftenartikelBotulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q58–K59 Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities In the recent past, about 40 botulinum neurotoxin (BoNT) subtypes belonging to serotypes A, B, E, and F pathogenic to humans were identified among hundreds of independent isolates. BoNTs are the etiological factors of ...