Browsing Artikel in Fachzeitschriften by Title
Now showing items 624-643 of 3855
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2014-11-13ZeitschriftenartikelComplete Nucleotide Sequence of a Citrobacter freundii Plasmid Carrying KPC-2 in a Unique Genetic Environment The complete and annotated nucleotide sequence of a 54,036-bp plasmid harboring a blaKPC-2 gene that is clonally present in Citrobacter isolates from different species is presented. The plasmid belongs to incompatibility ...
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2020-10-17ZeitschriftenartikelCompleteness of tuberculosis case notifications in Germany in 2013–2017: first results of an inventory study Background Evaluating the completeness of tuberculosis (TB) notification data is important for monitoring of TB surveillance systems. We conducted an inventory study to calculate TB underreporting in Germany in ...
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2013-01-01ZeitschriftenartikelComplexity of Botulinum Neurotoxins: Challenges for Detection Technology The detection of botulinum neurotoxins (BoNT) is extremely challenging due to their high toxicity and the multiple BoNT variants. To date, seven serotypes with more than 30 subtypes have been described, and even more ...
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2010-09-01ZeitschriftenartikelComplications of varicella after implementation of routine childhood varicella vaccination in Germany. A country-wide sentinel surveillance system was initiated in Germany after implementation of routine varicella vaccination of children >11 months. Sentinel physicians report monthly the number of cases and of severe varicella ...
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2017-09-12ZeitschriftenartikelComprehensive assessment of food and nutrient intake of children and adolescents in Germany: EsKiMo II – the eating study as a KiGGS module Background: As part of the second wave of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS Wave 2), food and nutrient intake of children and adolescents aged 6–17 years living in ...
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2022-12-21ZeitschriftenartikelComprehensive evaluation of peptide de novo sequencing tools for monoclonal antibody assembly Monoclonal antibodies are biotechnologically produced proteins with various applications in research, therapeutics and diagnostics. Their ability to recognize and bind to specific molecule structures makes them essential ...
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2015-03-12ZeitschriftenartikelComprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40 Background: Enterococcus faecalis is a multifaceted microorganism known to act as a beneficial intestinal commensal bacterium. It is also a dreaded nosocomial pathogen causing life-threatening infections in hospitalised ...
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2019-12-09ZeitschriftenartikelComputational pan-genome mapping and pairwise SNP-distance improve detection of Mycobacterium tuberculosis transmission clusters Next-generation sequencing based base-by-base distance measures have become an integral complement to epidemiological investigation of infectious disease outbreaks. This study introduces PANPASCO, a computational pan-genome ...
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2020-11-04ZeitschriftenartikelComputational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. ...
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2016-09-01ZeitschriftenartikelConcordance between self-reported and measured HIV and hepatitis C virus infection status among people who inject drugs in Germany Background: People who inject drugs (PWID) are disproportionately affected by both HIV and hepatitis C infection (HCV). Awareness of infection status is essential to ensure linkage to appropriate healthcare for those ...
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2018-05-22ZeitschriftenartikelConditio sine qua non: Umwelt und Gesundheit
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2012-09-27ZeitschriftenartikelConfidence-based Somatic Mutation Evaluation and Prioritization Next generation sequencing (NGS) has enabled high throughput discovery of somatic mutations. Detection depends on experimental design, lab platforms, parameters and analysis algorithms. However, NGS-based somatic mutation ...
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2010-06-30ZeitschriftenartikelConfirmed Exposure to Tick-Borne Encephalitis Virus and Probable Human Cases of Tick-Borne Encephalitis in Central/Northern Anatolia, Turkey Tick-borne encephalitis virus (TBEV) is the aetiological agent of tick-borne encephalitis (TBE), a potentially fatal central nervous system infection of humans. TBE is endemic in many areas of Europe and Asia; however, ...
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2021-01-22ZeitschriftenartikelConsistency of Social Interactions in Sooty Mangabeys and Chimpanzees Predictability of social interactions can be an important measure for the social complexity of an animal group. Predictability is partially dependent on how consistent interaction patterns are over time: does the behavior ...
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2022-02-02ZeitschriftenartikelConstruction and validation of safe Clostridium botulinum Group II surrogate strain producing inactive botulinum neurotoxin type E toxoid Botulinum neurotoxins (BoNTs), produced by the spore-forming bacterium Clostridium botulinum, cause botulism, a rare but fatal illness affecting humans and animals. Despite causing a life-threatening disease, BoNT is a ...
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2011-07-27ZeitschriftenartikelConstruction of a lytically replicating Kaposi's sarcoma-associated herpesvirus (KSHV) Karposi's sarcoma-associated herpesvirus (KSHV) is found predominantly in a latent state in most cell types, impeding investigations of the lytic replication cycle. Here, we engineered the cloned KSHV genome, bacterial ...
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2018-03-14ZeitschriftenartikelConstruction of a New Phage Integration Vector pFIV-Val for Use in Different Francisella Species We recently identified and described a putative prophage on the genomic island FhaGI-1 located within the genome of Francisella hispaniensis AS02-814 (F. tularensis subsp. novicida-like 3523). In this study, we constructed ...
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2017-03-23ZeitschriftenartikelContact investigation after a fatal case of extensively drug-resistant tuberculosis (XDR-TB) in an aircraft, Germany, July 2013 In July 2013, a passenger died of infectious extensively drug-resistant tuberculosis (XDR-TB) on board of an aircraft after a 3-hour flight from Turkey to Germany. Initial information indicated the patient had moved about ...
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2014-03-17ZeitschriftenartikelContact Investigation for Imported Case of Middle East Respiratory Syndrome, Germany On March 19, 2013, a patient from United Arab Emirates who had severe respiratory infection was transferred to a hospital in Germany, 11 days after symptom onset. Infection with Middle East respiratory syndrome coronavirus ...
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2013-02-21ZeitschriftenartikelContact investigation of a case of human novel coronavirus infection treated in a German hospital, October-November 2012 On 24 October 2012, a patient with acute respiratory distress syndrome of unknown origin and symptom onset on 5 October was transferred from Qatar to a specialist lung clinic in Germany. Late diagnosis on 20 November of ...