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Anzeige der Publikationen 12701-12720 von 13113
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2007-07-18ZeitschriftenartikelPopulation and antenatal-based HIV prevalence estimates in a high contracepting female population in rural South Africa Background: To present and compare population-based and antenatal-care (ANC) sentinel surveillance HIV prevalence estimates among women in a rural South African population where both provision of ANC services and family ...
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2007-07-03ZeitschriftenartikelFirst international diagnostic accuracy study for the serological detection of West Nile virus infection Background: The diagnosis of an acute or convalescent West Nile (WN) virus infection can be confirmed by various serological assays such as enzyme immunoassay (EIA), immunofluorescence assay (IFA), or neutralisation test ...
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2007-05-25ZeitschriftenartikelAccumulation of Pathological Prion Protein PrPSc in the Skin of Animals with Experimental and Natural Scrapie Prion infectivity and its molecular marker, the pathological prion protein PrPSc, accumulate in the central nervous system and often also in lymphoid tissue of animals or humans affected by transmissible spongiform ...
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2008-11-30ZeitschriftenartikelLyme-Borreliose: Forschungsbedarf und Forschungsansätze Lyme borreliosis: Research gaps and research approachesDie Lyme-Borreliose ist in der nördlichen Hemisphäre nach aktuellem Kenntnisstand die häufigste durch Zecken übertragene Infektionskrankheit. Deutschland ist neben anderen europäischen Ländern ein Hochendemie-Gebiet, daher ...
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2008-11-30ZeitschriftenartikelMit Wasser und Seife gegen die Grippe Fighting the flu with soap and water.Pharmazeutische Maßnahmen wie die Impfung und die antivirale Prophylaxe sind nur 2 Bausteine zum Infektionsschutz der Bevölkerung. Ein dritter, entscheidender Baustein sind einfache, nicht-pharmazeutische Maßnahmen wie die ...
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2009-11-12ZeitschriftenartikelClostridium difficile ribotypes 001, 017, and 027 are associated with lethal C. difficile infection in Hesse, Germany From January 2008 to April 2009, 72 cases of severe Clostridium difficile infection were reported from 18 different districts in the state of Hesse, Germany. A total of 41 C. difficile isolates from 41 patients were subjected ...
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2007-11-15ZeitschriftenartikelA case of Clostridium difficile-associated disease due to the highly virulent clone of Clostridium difficile PCR ribotype 027, March 2007 in Germany
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2009-02-26ZeitschriftenartikelCapability of the viral NS1 proteins to bind to the cellular adaptor proteins Crk and CrkL determines sensitivity of influenza viruses to Crk/CrkL expression
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2009-05-14ZeitschriftenartikelDetection of hepatitis E virus in wild boars of rural and urban regions in Germany and whole genome characterization of an endemic strain Background: Hepatitis E is an increasingly diagnosed human disease in Central Europe. Besides domestic pigs, in which hepatitis E virus (HEV) infection is highly prevalent, wild boars have been identified as a possible ...
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2009-05-20ZeitschriftenartikelTracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach Background: The prevalence and the origin of HIV-1 subtype B, the most prevalent circulating clade among the long-term residents in Europe, have been studied extensively. However the spatial diffusion of the epidemic ...
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2009-06-18ZeitschriftenartikelStudies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane protein The glycosylated membrane protein M of the severe acute respiratory syndrome associated coronavirus (SARS-CoV) is the main structural component of the virion and mediates assembly and budding of viral particles. The membrane ...
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2009-08-26ZeitschriftenartikelMeasuring adolescents' HRQoL via self reports and parent proxy reports: an evaluation of the psychometric properties of both versions of the KINDL-R instrument Background: Several instruments are available to assess children's health-related quality of life (HRQoL) based on self reports as well as proxy reports from parents. Previous studies have found only low-to-moderate ...
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2009-10-16ZeitschriftenartikelLack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients Background: A novel gammaretrovirus named xenotropic murine leukemia virus-related virus (XMRV) has been recently identified and found to have a prevalence of 40% in prostate tumor samples from American patients carrying ...
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2008-07-23ZeitschriftenartikelCCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual Background: Homozygosity (Δ32/Δ32) for the 32 bp deletion in the chemokine receptor 5 (CCR5) gene is associated with strong resistance against HIV infection. Heterozygosity is associated with protection of HIV-1 disease ...
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2009-01-08ZeitschriftenartikelTyping Clostridium difficile strains based on tandem repeat sequences Background: Genotyping of epidemic Clostridium difficile strains is necessary to track their emergence and spread. Portability of genotyping data is desirable to facilitate inter-laboratory comparisons and epidemiological ...
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2009-04-24ZeitschriftenartikelExploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release Background: The ALG2-interacting protein X (ALIX)/AIP1 is an adaptor protein with multiple functions in intracellular protein trafficking that plays a central role in the biogenesis of enveloped viruses. The ubiquitin ...
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2009-04-20ZeitschriftenartikelInvasive Haemophilus influenzae infections in Germany: impact of non-type b serotypes in the post-vaccine era Background: Haemophilus influenzae type b (Hib) vaccination led to a significant decrease in invasive bacterial infections in children. The aim of this study was to assess a potential shift to more non-type b invasive ...
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2009-10-29ZeitschriftenartikelSociodemographic differences in return to work after stroke: the South London Stroke Register (SLSR) Background: Loss of employment contributes significantly to the burden of stroke on individuals and society. There is limited information on factors influencing return to work after stroke. Objectives: To investigate the ...
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2009-07-13ZeitschriftenartikelAdding to Yersinia enterocolitica Gene Pool Diversity: Two Cryptic Plasmids from a Biotype 1A Isolate We report the nucleotide sequence of two novel cryptic plasmids (4357 and 14 662 base pairs) carried by a Yersinia enterocolitica biotype 1A strain isolated from pork. As distinguished from most biotype 1A strains, this ...
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2009-10-27ZeitschriftenartikelActivation of the Antiviral Kinase PKR and Viral Countermeasures The interferon-induced double-stranded (ds)RNA-dependent protein kinase (PKR) limits viral replication by an eIF2-mediated block of translation. Although many negative-strand RNA viruses activate PKR, the responsible ...