Auflistung Artikel in Fachzeitschriften nach Titel
Anzeige der Publikationen 3090-3109 von 3404
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2011-01-01ZeitschriftenartikelTowards an AIDS vaccine: The transmembrane envelope protein as target for broadly neutralizing antibodies Although the development of an effective vaccine is the main goal in the fight against AIDS, all attempts by numerous laboratories to develop a vaccine have failed so far. In addition, it is still unclear whether cytotoxic ...
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2013-03-11ZeitschriftenartikelTowards further reduction and replacement of animal bioassays in prion research by cell and protein misfolding cyclic amplification assays Laboratory animals have long since been used extensively in bioassays for prions in order to quantify, usually in terms of median infective doses [ID50], how infectious these pathogens are in vivo. The identification of ...
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2021-06-01ZeitschriftenartikelTowards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach Small proteins play essential roles in bacterial physiology and virulence, however, automated algorithms for genome annotation are often not yet able to accurately predict the corresponding genes. The accuracy and reliability ...
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2019-05-23ZeitschriftenartikelToxoplasmosis in Germany: Epidemiology, Diagnosis, Risk Factors, and Treatment Background: With approximately 30% of the world population infected, Toxoplasma gondii is one of the most widespread pathogenic parasites in both humans and animals and a major problem for health economics in many ...
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2009-05-20ZeitschriftenartikelTracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach Background: The prevalence and the origin of HIV-1 subtype B, the most prevalent circulating clade among the long-term residents in Europe, have been studied extensively. However the spatial diffusion of the epidemic ...
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2015-10-07ZeitschriftenartikelTracing the Spread of Clostridium difficile Ribotype 027 in Germany Based on Bacterial Genome Sequences We applied whole-genome sequencing to reconstruct the spatial and temporal dynamics underpinning the expansion of Clostridium difficile ribotype 027 in Germany. Based on re-sequencing of genomes from 57 clinical C. difficile ...
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2018-09-26ZeitschriftenartikelTracking of Blood Pressure in Children and Adolescents in Germany in the Context of Risk Factors for Hypertension Blood pressure (BP) tracking from childhood to adulthood has two aspects: the ranking stability relative to others over time and the prediction of future values. This study investigates BP tracking in children and adolescents ...
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2021-05-19ZeitschriftenartikelTracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using ...
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2009-08-06ZeitschriftenartikelTranscription of the phage-encoded Panton–Valentine leukocidin of Staphylococcus aureus is dependent on the phage life-cycle and on the host background Panton-Valentine leukocidin (PVL) is a pore-forming, bi-component toxin secreted by Staphylococcus aureus strains epidemiologically associated with diseases such as necrotizing pneumonia and skin and soft-tissue infections. ...
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2017-06-07ZeitschriftenartikelTranslational Rodent Models for Research on Parasitic Protozoa—A Review of Confounders and Possibilities Rodents, in particular Mus musculus, have a long and invaluable history as models for human diseases in biomedical research, although their translational value has been challenged in a number of cases. We provide some ...
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2013-12-12ZeitschriftenartikelTransmission and molecular characterisation of wild measles virus in Romania, 2008 to 2012 Molecular characterisation of measles virus is a powerful tool for tracing transmission. Genotyping may prove the absence of endemic circulation of measles virus, i.e. transmission for more than 12 months, which is one of ...
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2009-12-04ZeitschriftenartikelTransmission dynamics of pulmonary tuberculosis between autochthonous and immigrant sub-populations Background: The overall incidence of tuberculosis (TB) in Western Europe has been declining since the 19th Century. However, immigrant sub-groups from high-prevalence countries are slowing down this trend. The aim of this ...
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2009-11-15ZeitschriftenartikelTransmission of Drug‐Resistant HIV‐1 is Stabilizing in Europe The SPREAD Programme investigated prospectively the time trend from September 2002 through December 2005 of transmitted drug resistance (TDR) among 2793 patients in 20 European countries and in Israel with newly diagnosed ...
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2019-07-16ZeitschriftenartikelTransmission of Porcine Circovirus 3 (PCV3) by Xenotransplantation of Pig Hearts into Baboons Porcine circovirus 3 (PCV3) is a newly described member of the virus family Circoviridae. PCV3 is highly distributed among pigs and wild boars worldwide. A sudden introduction of PCV3 was recently observed in a herd of ...
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2015-08-27ZeitschriftenartikelTransmission patterns of human enterovirus 71 to, from and among European countries, 2003 to 2013 Enterovirus 71 (EV-71) is involved in epidemics of hand, foot, and mouth disease (HFMD) and has been reported to occur with severe neurological complications in eastern and south-east Asia. In other geographical areas, the ...
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2009-10-06ZeitschriftenartikelTransmission routes and risk factors for autochthonous hepatitis E virus infection in Europe: a systematic review Increasing numbers of non-travel-associated hepatitis E virus (HEV) infections have been reported in Europe in recent years. Our objective was to review the evidence on risk factors and transmission routes of autochthonous ...
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2023-10-10ZeitschriftenartikelTransmitted drug resistance and subtype patterns of viruses from reported new HIV diagnoses in Germany, 2017–2020 Background The transmission of resistant HIV variants jeopardizes the effective use of antiretrovirals for therapy and prophylaxis. Molecular surveillance of new HIV diagnoses with a focus on prevalence and type of ...
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2016-12-20ZeitschriftenartikelTransspecies Transmission of Gammaretroviruses and the Origin of the Gibbon Ape Leukaemia Virus (GaLV) and the Koala Retrovirus (KoRV) Transspecies transmission of retroviruses is a frequent event, and the human immunodeficiency virus-1 (HIV-1) is a well-known example. The gibbon ape leukaemia virus (GaLV) and koala retrovirus (KoRV), two gammaretroviruses, ...
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2018-05-31ZeitschriftenartikelTravel-associated hepatitis A in Europe, 2009 to 2015 Background: Travel to countries with high or intermediate hepatitis A virus (HAV) endemicity is a risk factor for infection in residents of countries with low HAV endemicity. Aim: The objective of this study was to ...
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2013-06-06ZeitschriftenartikelTravel-associated Legionnaires’ disease in Europe, 2010 In 2010, the European surveillance network for travel-associated Legionnaires’ disease (ELDSNet, previously EWGLINET) received reports of 864 cases of travel-associated Legionnaires’ disease, of whom 24 were reported to ...