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Anzeige der Publikationen 12741-12760 von 13125
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2008-03-28ZeitschriftenartikelDie Entwicklung des Bundesinstituts für Arzneimittel und Medizinprodukte (BfArM) im zunehmenden europäischen Wettbewerb. Das Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) ist unter anderem verantwortlich für die Zulassung von wirksamen und unbedenklichen Arzneimitteln (AM) sowie für die Überwachung von Arzneimittelrisiken ...
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2008-05-14ZeitschriftenartikelPersonale, familiäre und soziale Schutzfaktoren und gesundheitsbezogene Lebensqualität chronisch kranker Kinder und Jugendlicher. Die vorliegende Arbeit beschreibt auf der Grundlage der bundesweit repräsentativen Daten des Kinder- und Jugendgesundheitssurvey (KiGGS) die chronischen Gesundheitsstörungen Asthma, Adipositas und ADHS bei Kindern und ...
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2008-09-05ZeitschriftenartikelMolekulare Analyse humaner Influenzaviren Die Evolution der Influenzaviren wird in zunehmendem Umfang außer mittels klassischer Methoden über molekulare Verfahren verfolgt. Im Vordergrund steht dabei die Analyse der beiden Hüllantigene Hämagglutinin (HA) und ...
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2009-10-18ZeitschriftenartikelProtective measures and H5N1-seroprevalence among personnel tasked with bird collection during an outbreak of avian influenza A/H5N1 in wild birds, Ruegen, Germany, 2006 Background: In Germany, the first outbreak of highly pathogenic avian influenza A/H5N1 occurred among wild birds on the island of Ruegen between February and April 2006. The aim of this study was to investigate the ...
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2009-08-06ZeitschriftenartikelDescription of the early stage of pandemic (H1N1) 2009 in Germany, 27 April-16 June 2009 We report characteristics of the early stage of the pandemic (H1N1) 2009 in Germany. Until 16 June 2009, 198 confirmed cases were notified. Almost half of the cases (47%) were imported, mostly from Mexico and the United ...
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2009-08-27ZeitschriftenartikelNasal Colonization of Humans with Methicillin-Resistant Staphylococcus aureus (MRSA) CC398 with and without Exposure to Pigs Background: Studies in several European countries and in North America revealed a frequent nasal colonization of livestock with MRSA CC398 and also in humans with direct professional exposure to colonized animals. The ...
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2009-01-22ZeitschriftenartikelCluster of hepatitis A cases among travellers returning from Egypt, Germany, September through November 2008 From September to November 2008, 34 cases of hepatitis A imported from Egypt were reported to the German public health authorities. Investigations point to a continuing common source of infection, most likely linked to ...
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2007-05-09ZeitschriftenartikelScrapie Agent (Strain 263K) Can Transmit Disease via the Oral Route after Persistence in Soil over Years The persistence of infectious biomolecules in soil constitutes a substantial challenge. This holds particularly true with respect to prions, the causative agents of transmissible spongiform encephalopathies (TSEs) such as ...
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2005-01-05ZeitschriftenartikelAn international comparative study of blood pressure in populations of European vs. African descent Background: The consistent finding of higher prevalence of hypertension in US blacks compared to whites has led to speculation that African-origin populations are particularly susceptible to this condition. Large surveys ...
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2007-04-10ZeitschriftenartikelThe current MLVA typing scheme for Enterococcus faecium is less discriminatory than MLST and PFGE for epidemic-virulent, hospital-adapted clonal types Background: MLVA (multiple-locus variable-number tandem repeat analysis) is a reliable typing technique introduced recently to differentiate also isolates of Enterococcus faecium. We used the established VNTR (variable ...
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2007-12-03ZeitschriftenartikelTherapy-refractory Panton Valentine Leukocidin-positive community-acquired methicillin-sensitive Staphylococcus aureus sepsis with progressive metastatic soft tissue infection: a case report We report a case of fulminant multiple organ failure including the Acute Respiratory Distress Syndrome (ARDS), haemodynamic, and renal failure due to community-acquired methicillin-sensitive Panton Valentine Leukocidin ...
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2009-08-27ZeitschriftenartikelInfluenza A(H1N1)v in Germany: the first 10,000 cases The analysis of the first 10,000 cases of influenza A(H1N1)v in Germany confirms findings from other sources that the virus is currently mainly causing mild diseases, affecting mostly adolescents and young adults. Overall ...
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2007-09-13ZeitschriftenartikelProtracted outbreak of S. Enteritidis PT 21c in a large Hamburg nursing home Background: During August 2006, a protracted outbreak of Salmonella (S.) Enteritidis infections in a large Hamburg nursing home was investigated. Methods: A site visit of the home was conducted and food suppliers' premises ...
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2009-09-03ZeitschriftenartikelCowpox Virus Outbreak in Banded Mongooses (Mungos mungo) and Jaguarundis (Herpailurus yagouaroundi) with a Time-Delayed Infection to Humans Background: Often described as an extremely rare zoonosis, cowpox virus (CPXV) infections are on the increase in Germany. CPXV is rodent-borne with a broad host range and contains the largest and most complete genome of ...
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2009-04-20ZeitschriftenartikelMalaria transmission in non-endemic areas: case report, review of the literature and implications for public health management In non-endemic areas, malaria is rare and locally acquired infections, particularly with Plasmodium falciparum, are exceptional events. The diagnosis is, therefore, likely to be delayed or missed in patients without a ...
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2009-06-11ZeitschriftenartikelEstimating the regional distribution of men who have sex with men (MSM) based on Internet surveys Background: Measurement of prevalence and incidence of infections in a hard to reach population like men who have sex with men (MSM) is hampered by its unknown size and regional distribution. Population-based surveys ...
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2009-06-11ZeitschriftenartikelThe denominator problem: Estimating MSM-specific incidence of sexually transmitted infections and prevalence of HIV using population sizes of MSM derived from Internet surveys Background: Measuring prevalence and incidence of sexually transmitted infections in hard to reach populations like men who have sex with men (MSM) is hampered by unknown size and regional distribution of this population. ...
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2005-01-24ZeitschriftenartikelGenetical and functional investigation of fliC genes encoding flagellar serotype H4 in wildtype strains of Escherichia coli and in a laboratory E. coli K-12 strain expressing flagellar antigen type H48 Background: Serotyping of O-(lipopolysaccharide) and H-(flagellar) antigens is a wideley used method for identification of pathogenic strains and clones of Escherichia coli. At present, 176 O- and 53 H-antigens are ...
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2008-11-21ZeitschriftenartikelThe Hyphal-Associated Adhesin and Invasin Als3 of Candida albicans Mediates Iron Acquisition from Host Ferritin Iron sequestration by host iron-binding proteins is an important mechanism of resistance to microbial infections. Inside oral epithelial cells, iron is stored within ferritin, and is therefore not usually accessible to ...
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2009-06-21ZeitschriftenartikelRole of complement and antibodies in controlling infection with pathogenic simian immunodeficiency virus (SIV) in macaques vaccinated with replication-deficient viral vector Background: We investigated the interplay between complement and antibodies upon priming with single-cycle replicating viral vectors (SCIV) encoding SIV antigens combined with Adeno5-SIV or SCIV pseudotyped with murine ...