edoc.rki.de - Open Access Publikationsserver: Neuzugänge
Anzeige der Publikationen 10941-10960 von 13089
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2015-11-26ZeitschriftenartikelPreface Biological Toxins—Ancient Molecules Posing a Current Threat
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2015-11-26ZeitschriftenartikelRecommended Immunological Strategies to Screen for Botulinum Neurotoxin-Containing Samples Botulinum neurotoxins (BoNTs) cause the life-threatening neurological illness botulism in humans and animals and are divided into seven serotypes (BoNT/A–G), of which serotypes A, B, E, and F cause the disease in humans. ...
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2015-11-26ZeitschriftenartikelActivation of the Mitochondrial Apoptotic Signaling Platform during Rubella Virus Infection Mitochondria- as well as p53-based signaling pathways are central for the execution of the intrinsic apoptotic cascade. Their contribution to rubella virus (RV)-induced apoptosis was addressed through time-specific evaluation ...
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2015-11-26ZeitschriftenartikelGeneration and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test The detection and identification of botulinum neurotoxins (BoNT) is complex due to the existence of seven serotypes, derived mosaic toxins and more than 40 subtypes. Expert laboratories currently use different technical ...
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2015-10-26ZeitschriftenartikelRecommended Immunological Assays to Screen for Ricin-Containing Samples Ricin, a toxin from the plant Ricinus communis, is one of the most toxic biological agents known. Due to its availability, toxicity, ease of production and absence of curative treatments, ricin has been classified by the ...
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2015-11-26ZeitschriftenartikelQualitative and Quantitative Detection of Botulinum Neurotoxins from Complex Matrices: Results of the First International Proficiency Test In the framework of the EU project EQuATox, a first international proficiency test (PT) on the detection and quantification of botulinum neurotoxins (BoNT) was conducted. Sample materials included BoNT serotypes A, B and ...
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2015-11-26ZeitschriftenartikelCharacterization of Ricin and R. communis Agglutinin Reference Materials Ricinus communis intoxications have been known for centuries and were attributed to the toxic protein ricin. Due to its toxicity, availability, ease of preparation, and the lack of medical countermeasures, ricin attracted ...
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2015-11-26ZeitschriftenartikelAn International Proficiency Test to Detect, Identify and Quantify Ricin in Complex Matrices While natural intoxications with seeds of Ricinus communis (R. communis) have long been known, the toxic protein ricin contained in the seeds is of major concern since it attracts attention of those intending criminal, ...
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2015-11-03ZeitschriftenartikelIn vitro activity of ceftobiprole against key pathogens associated with pneumonia in hospitalized patients: results from the PEG surveillance study, 2010 Empirical treatment of hospital-acquired pneumonia (HAP) has increasingly been threatened by methicillin-resistant Staphylococcus aureus (MRSA) and multidrug resistant Gram-negative pathogens. In contrast, empirical treatment ...
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2015-12-17ZeitschriftenartikelOngoing outbreak of invasive listeriosis, Germany, 2012 to 2015 Listeriosis patient isolates in Germany have shown a new identical pulsed-field gel electrophoresis (PFGE) pattern since 2012 (n = 66). Almost all isolates (Listeria monocytogenes serotype 1/2a) belonged to cases living ...
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2015-11-19ZeitschriftenartikelComplete Genome Sequence of the Gut Commensal and Laboratory Strain Enterococcus faecium 64/3 The genome sequence of the commensal and widely used laboratory strain Enterococcus faecium 64/3 was resolved by means of PacificBioscience and Illumina whole-genome sequencing. The genome comprises 2,575,333 bp with 2,382 ...
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2015-11-23ZeitschriftenartikelRisk Factors for Sporadic Non-Pregnancy Associated Listeriosis in Germany — Immunocompromised Patients and Frequently Consumed Ready-To-Eat Products Non-pregnancy associated (N-PA) listeriosis, caused by Listeria monocytogenes, is a rare but severe disease, and is predominantly food-borne. Most cases appear sporadic and their infection vehicle remains unknown. Incidence ...
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2015-10-20ZeitschriftenartikelHemoparasites in a wild primate: Infection patterns suggest interaction of Plasmodium and Babesia in a lemur species Hemoparasites can cause serious morbidity in humans and animals and often involve wildlife reservoirs. Understanding patterns of hemoparasite infections in natural populations can therefore inform about emerging disease ...
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2015-07-31ZeitschriftenartikelHighly Virulent Non-O157 Enterohemorrhagic Escherichia coli (EHEC) Serotypes Reflect Similar Phylogenetic Lineages, Providing New Insights into the Evolution of EHEC Enterohemorrhagic Escherichia coli (EHEC) is the causative agent of bloody diarrhea and extraintestinal sequelae in humans, most importantly hemolytic-uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). ...
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2015-09-24ZeitschriftenartikelFirst Draft Genome Sequence of Balamuthia mandrillaris, the Causative Agent of Amoebic Encephalitis The free-living amoeba Balamuthia mandrillaris is a rare but highly lethal agent of amoebic encephalitis in humans and many other mammalian species. Here, we announce the first draft genome sequence of the original 1990 ...
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2015-08-17ZeitschriftenartikelZöliakieprävalenz bei Kindern und Jugendlichen in Deutschland Hintergrund: Eine nicht behandelte Zöliakie geht mit erhöhter Morbidität und Mortalität einher. Für Kinder und Jugendliche in Deutschland gibt es keine aktuellen Zahlen zur Prävalenz der Zöliakie und zum Anteil nicht ...
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2015-10-07ZeitschriftenartikelTracing the Spread of Clostridium difficile Ribotype 027 in Germany Based on Bacterial Genome Sequences We applied whole-genome sequencing to reconstruct the spatial and temporal dynamics underpinning the expansion of Clostridium difficile ribotype 027 in Germany. Based on re-sequencing of genomes from 57 clinical C. difficile ...
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2015-11-19ZeitschriftenartikelChanges in diabetes care indicators: findings from German National Health Interview and Examination Surveys 1997–1999 and 2008–2011 Objectives: To investigate changes in type 2 diabetes care indicators over time in Germany. Methods: Adults aged 45–79 years with type 2 diabetes were identified from two national health examination surveys conducted ...
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2015-12-10ZeitschriftenartikelTuberculosis treatment outcome in the European Union and European Economic Area: an analysis of surveillance data from 2002‒2011 Monitoring the treatment outcome (TO) of tuberculosis (TB) is essential to evaluate the effectiveness of the intervention and to identify potential barriers for TB control. The global target is to reach a treatment success ...
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2015-12-14ZeitschriftenartikelErgebnisse einer Onlinebefragung zum Tuberkulose-Bericht des RKI